Ergothioneine hmoov(EGT) yog ib qho tshwm sim ib txwm muaj amino acid thawj zaug cais tawm ntawm cov kab mob ergot hauv xyoo 1909 los ntawm Fabkis tus kws muag tshuaj Charles Tanret thiab muaj npe tom qab cov fungus. Txawm li cas los xij, nws tsis tuaj yeem tsim los ntawm lub cev nws tus kheej thiab tsuas yog tau los ntawm kev noj haus, nrog cov nceb yog cov khoom noj tseem ceeb.
Cov teebmeem antioxidant:
(1) Nws muaj peev xwm tiv thaiv cov tiam ntawm OH thiab lwm yam dawb radicals nrog rau ncaj qha scavenge reactive oxygen hom (ROS) xws li hypochlorous acid thiab peroxynitrite.
2) Nws tuaj yeem ua tau zoo chelate ntau yam divalent hlau cations;
3) Nws tuaj yeem cuam tshuam nrog lwm cov tshuaj tiv thaiv antioxidant hauv lub cev. Piv txwv suav nrog kev ua kom muaj cov kab mob hauv cov kab mob antioxidant uas cuam tshuam nrog MAPKs thiab kev tswj hwm ntawm peroxidase thiab antioxidant enzyme qib;
4) Inhibits oxidation ntawm ntau yam hemoglobin.
Dab tsi yog Qhov Zoo Ntawm Ergothioneine Powder?
1) Nws yog ib qho adaptive antioxidant. Nws yuav nyiam nyob rau hauv cov hlwb thiab cov ntaub so ntswg raug oxidative kev nyuaj siab thiab puas. Cov organic cation transporter protein OCTN1 (tam sim no hu ua SLC22A4, 551 amino acid transporter protein nrog peb qhov glycosylation) hauv tib neeg lub cev thauj ergothioneine mus rau qhov chaw xav tau;
2) Tib neeg lub cev muaj txoj hauv kev rov ua dua tshiab rau ergothioneine. Kev khi ntawm ergothioneine rau glutathione tuaj yeem rov tsim dua nws kom nws tuaj yeem ua voj voog thiab hnov mob nrog ib leeg-linear oxygen kom ua tiav cov txiaj ntsig zoo dua thiab ntev-ntev antioxidant;
3) Ergothioneine raug tso tawm qeeb heev hauv lub cev, yog li ergothioneine tuaj yeem khaws cia hauv cov ntaub so ntswg hauv lub cev thiab cov qe ntshav liab ntawm tib neeg thiab lwm yam tsiaj kom siv nws cov teebmeem. Nws muaj nyob rau hauv daim ntawv ntawm thione thiab muaj zoo tagnrho thermal thiab pH stability.
Lub peev xwm mechanisms ntawm kev txiav txim ntawm ergothioneine ntawm cov kab mob neurodegenerative muaj ntau yam:
1) Ergothioneine tuaj yeem cuam tshuam ncaj qha rau kev sib sau ntawm cov kab mob thiab A hauv hippocampus thiab lipid peroxidation hauv cov hlwb neuronal;
2) Nws tuaj yeem cuam tshuam rau lwm yam antioxidants. Piv txwv suav nrog kev tswj hwm qhov sib piv ntawm GSH / GSSG thiab superoxide dismutase kev ua haujlwm thiab rov ua haujlwm acetylcholinesterase hauv lub hlwb;
3) Nws tiv thaiv kev tsim ntawm peroxynitrite.
4) Nws tuaj yeem txo qis ROS theem ncaj qha thiab cuam tshuam txoj kev hloov pauv ntawm NF-κB.
Dab tsi yog Cov Haujlwm Ntawm Ergothioneine hmoov Ntawm Kev Kho Mob?
Vim nws lub peev xwm tshwj xeeb antioxidant, ergothioneine tau dhau los ua cov khoom muaj peev xwm tiv thaiv kev laus hauv kev lag luam tu tawv nqaij. Nyob rau hauv "2022 Muaj Peev Xwm Cov Khoom Sau Npe", ergothioneine yog qeb thib cuaj muaj peev xwm. Tsis tas li ntawd, kev kho kom zoo nkauj kho cov ntaub ntawv loj cov ntaub ntawv tseem ceeb los tiv thaiv kev laus hauv cov khoom siv tiv thaiv kev laus ntawm daim tawv nqaij ua ntaub ntawv loj hlob tus nqi, ergothioneine nrog 64.2 feem pua txoj kev loj hlob nyob rau qib yim.
Kev saib xyuas ntawm daim tawv nqaij ntawm ergothioneine yog qhov tseem ceeb hauv kev tiv thaiv kev laus, thiab nws cov txheej txheem ntawm kev ua haujlwm muaj 5 lub ntsiab lus tseem ceeb hauv qab no:
1) Anti-photo-aging. Nws tuaj yeem tiv thaiv ultraviolet (UV), inhibit UV-induced peroxidation, inflammatory yam / -Gel, MMPs qhia.
2) Antioxidant. Tiv thaiv oxidative puas tsuaj, kho DNA puas, inhibits qhov pib ntawm apoptosis, thiab ua rau kom cov cell viability;
3) Anti-glycation, txo cov tiam ntawm AGEs;
4) Kev tiv thaiv ntawm mitochondrial membrane muaj peev xwm thiab tDNA puas;
5) tiv thaiv kev puas tsuaj telomere, ua kom cov haujlwm telomerase thiab txo qis telomere luv luv.
Tsis tas li ntawd, ergothioneine tau pom tias muaj txiaj ntsig zoo hauv kev tiv thaiv qhov muag, txhim kho cov hlab plawv thiab kho cov leeg.
Synthetic Biology Ntawm Ergothioneine Powder
Ergothioneine tuaj yeem tau txais peb txoj hauv kev: nceb extraction, tshuaj synthesis thiab hluavtaws biology.
Mushroom extraction tau raug tso tseg vim nws cov ntsiab lus tsawg thiab tus nqi siab.
Cov tshuaj synthesis yog nquag rau chiral isomer impurities thiab hnyav residues, uas yog kim thiab muaj kev cuam tshuam rau ib puag ncig.
Tam sim no, ergothioneine feem ntau yog npaj los ntawm hluavtaws biology fermentation.
Nrog rau kev loj hlob sai ntawm hluavtaws biology, tus nqi ntawm ergothioneine yuav txo qis mus ntxiv. Thaum ergothioneine dhau los ua "muaj nqis" thiab cov kev cai txwv tsis pub dhau, ergothioneine yuav dhau los ua cov khoom muaj npe nrov xws li sodium hyaluronate yav tom ntej.
Peb txaus siab los muab peb cov kev txawj ntse hauv kev ua cov khoom ntuj ergothioneine hmoov nrog kev ua haujlwm zoo tshaj plaws. Peb cov peev txheej siab heev thiab muaj peev xwm ua rau peb ua tau ntau yam kev xav tau nrog qhov tseeb. Peb zoo siab tos txais cov lus nug thiab kev sib tham los ntawm txhua tus neeg txaus siab nrhiav kev koom nrog ergothioneine rau hauv lawv cov khoom lossis kev tshawb fawb. Yog xav paub ntxiv thiab kev sib txuas lus, thov tsis txhob yig tiv tauj peb ntawminfo@gybiotech.com. Peb pab neeg npaj txhij los pab koj thiab muab cov lus qhia tsim nyog kom ua tau raws li koj cov kev xav tau tshwj xeeb.
