Beta{0}}glucan poov xab hmoovyog siv rau hauv cov khoom noj dev. Cov pov thawj tam sim no qhia tau tias beta-glucan cov tshuaj los ntawm cov chaw tshwj xeeb (xws li Saccharomyces cerevisiae) thiab ntawm cov koob tshuaj tshwj xeeb (xws li 0.14% ntawm tag nrho cov khoom noj) muaj kev nyab xeeb siab rau cov neeg laus noj qab nyob zoo. Qhov no qhia tau hais tias muaj txiaj ntsig zoo hauv kev tswj lub plab microbiota, txhim kho cov protein digestibility, thiab hloov kev tiv thaiv kab mob. Txawm li cas los xij, kev soj ntsuam nruj heev yog tsim nyog rau cov tib neeg uas muaj kab mob hauv qab (tshwj xeeb yog kab mob plab hnyuv) lossis kev tiv thaiv kab mob.
Puas yog Beta-Glucan Safe Rau Cov dev?
Lub hauv paus ntawm kev ntsuas kev nyab xeeb ntawm beta-glucan poov xab hmoov yog nyob rau hauv kev nkag siab txog nws cov txheej txheem ntawm kev ua. Raws li cov kab mob- txuam nrog cov qauv molecular, -glucan siv nws cov teebmeem los ntawm kev khi rau cov receptors tshwj xeeb (xws li Dectin-1) ntawm lub cev tiv thaiv kab mob (xws li macrophages). Nws yog noteworthy tias -glucan tsis yog ib yam khoom uas tsim los ntawm lub cev dev nws tus kheej; yog li ntawd, nws tau lees paub los ntawm kev tiv thaiv kab mob raws li "tsis yog tus kheej" tivthaiv. Qhov kev lees paub no yog lub hauv paus lom neeg rau nws txoj haujlwm immunomodulatory thiab, nyob rau hauv tsawg zaus, muaj peev xwm ua rau muaj kev tiv thaiv kab mob ntau dhau.
Hauv cov dev noj qab nyob zoo, qhov kev lees paub no feem ntau ua rau muaj kev tiv thaiv cov lus teb tsis yog cov kab mob pathological. Piv txwv li, ib koob tshuaj- teb txoj kev tshawb fawb luam tawm hauv *Microorganisms* hauv 2024 qhia meej tias ntxiv 0.07% rau 0.28% purified -1,3/1,6-glucan rau kev noj haus ntawm cov neeg laus noj qab haus huv dev tsis ua rau muaj kev phiv tshuaj. Hauv txoj kev tshawb no, tsis muaj kev hloov pauv tsis zoo tau pom nyob rau hauv fecal pH, luv-chain fatty acid concentration, phagocytic kev ua, lossis lymphocyte subset suav hauv cov dev sim, lees tias muaj kev tiv thaiv siab nyob rau hauv cov koob tshuaj no.
Puas Muaj Kev Nyab Xeeb rau Cov dev?
Txawm hais tias beta-glucan poov xab hmoov muaj kev nyab xeeb zoo hauv cov tib neeg noj qab haus huv, cov ntaub ntawv xov xwm tsis ntev los no tau ua rau muaj kev txhawj xeeb txog nws kev siv hauv cov kab mob tshwj xeeb.
• rhiab heev rau cov neeg mob uas muaj kab mob plob tsis so tswj (IBD)
Cov ntaub ntawv tshaj tawm tau tshaj tawm hauv MDPI hauv xyoo 2026 cov ncauj lus kom ntxaws txog kev tsis zoo hauv ob tus dev nrog IBD tom qab kev tswj hwm qhov ncauj ntawm beta-glucan poov xab hmoov. Ob tus dev, uas nws cov xwm txheej tau pib tswj hwm, pom cov tawv nqaij hnyav anaphylaxis (erythema, papules) thiab khaus khaus tom qab beta- noj glucan. Cov kws tshawb fawb tau pom zoo tias kev ua haujlwm tsis zoo ntawm txoj hnyuv thiab kev ua rau lub qhov ncauj tsis zoo cuam tshuam nrog IBD tuaj yeem ua rau muaj qhov txawv txav Th2- hom kev tiv thaiv kab mob tsis zoo hauv kev teb rau beta-glucan.
• Kev rog rog thiab kev ua xua
Lwm qhov kev tshawb fawb ntawm cov dev rog rog tau pom tias 6-xyoo- laus rog sib xyaw- cov dev uas tsis muaj keeb kwm ntawm beta-glucan poov xab hmoov raug tsim cov tsos mob xws li plaub hau poob, erythema, thiab khaus khaus hnyav li ntawm 30 hnub tom qab noj cov zaub mov uas muaj 0.1% purified. -1,3/1,6-glucan. Cov tsos mob tshwm sim tom qab tshem tawm cov khoom xyaw no, tab sis rov tshwm sim thaum rov tshwm sim. Qhov tseem ceeb, tus dev tom qab pom cov tsos mob zoo sib xws rau -1,3-glucan muab los ntawm Euglena gracilis, qhia tias qhov kev tsis haum tshuaj no yuav muaj qhov sib txawv lossis tsis muaj kev tiv thaiv kab mob tshwj xeeb.
Yuav Ua Li Cas Ntxiv Beta-Glucan rau dev?
Kev txiav txim siab ntau npaum li cas muaj kev nyab xeeb yog ib kauj ruam tseem ceeb rau kev tsim cov khoom lag luam B2B. Ntau qhov kev tshawb fawb muab cov ntaub ntawv muaj txiaj ntsig zoo thiab kev siv tshuaj.
• Pom zoo noj tshuaj rau cov dev noj qab nyob zoo:
Kev tshawb fawb xyoo 2024 tau soj ntsuam beta-glucan poov xab hmoov extruded dev noj. Ib qho 0.14% -glucan ntxiv tau pom tias muaj txiaj ntsig zoo rau kev lom neeg. Nws txhawb kev loj hlob ntawm cov kab mob muaj txiaj ntsig, xws li Faecalibacterium thiab Prevotella. Nws kuj tseem txhim kho qhov pom meej digestibility ntawm cov protein tsis zoo. Txoj kev tshawb fawb ntxiv tau pom tias 0.28% qib ntxiv tseem nyob hauv thaj tsam nyab xeeb. Tsis muaj qhov txawv txav ntawm lub cev hloov pauv hauv cov dev.
• Lub cev hnyav-Raws li noj:
Cov kev tshawb fawb soj ntsuam kuj tau tshuaj xyuas ntau npaum li cas raws li lub cev hnyav. Ib txoj kev tshawb fawb tau siv qhov ncauj beta-glucan poov xab hmoov supplementation ntawm kwv yees li 9.13 ± 1.14 mg / kg lub cev qhov hnyav hauv cov dev uas tswj cov kab mob plab hnyuv. Lwm txoj kev tshawb fawb ntawm cov dev noj qab haus huv tau siv 1,000 mg / hnub ntawm POLYCAN, ib -glucan muab los ntawm Brachystomata buddingae. Cov txiaj ntsig tau pom tsis muaj qhov cuam tshuam tsis zoo rau kev loj hlob kev ua haujlwm, kev noj zaub mov zoo, lossis fecal pH. Cov kws tshawb fawb kuj tau soj ntsuam cov ntshav qab zib immunoglobulin G thiab insulin ntau ntxiv -zoo li qib kev loj hlob-1.
Yog tias koj yog cov chaw tsim khoom noj dev, tsim cov khoom noj tsiaj cov khoom noj tuaj yeem siv cov kev tshawb fawb dev noj qab haus huv raws li kev siv. Thawj theem ntxiv ntawm 0.1% - 0.2% yog pom zoo. Digestibility yuav tsum tau txheeb xyuas raws li qhov tshwj xeeb formulation. Thaum xaiv beta-glucan poov xab hmoov cov chaw muag khoom, cov tuam txhab yuav tsum ua tib zoo tshuaj xyuas cov hlau hnyav, txwv tsis pub microbial, thiab cov ntaub ntawv kuaj mycotoxin. Guanjie Biotech's Poov Beta Glucan Powder tau dhau los ua cov ntawv pov thawj zoo. Qhov no yuav pab kom batch-rau-batch sib xws, siab purity, thiab txo cov khoom raw khoom txaus ntshai.
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Cov dev |
Kev soj ntsuam kev nyab xeeb |
Cov ntaub ntawv tseem ceeb / Cov lus xaus |
Cov lus pom zoo ua lag luam: |
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Noj qab nyob zoo tus dev |
Siab |
Qhov pom zoo koob tshuaj ntxiv yog 0.14%. Ntawm qhov koob tshuaj no, kev zom cov protein ntau tau txhim kho, butyrate - tsim cov kab mob uas muaj txiaj ntsig zoo (xws li Faecalibacterium) tau ua kom muaj txiaj ntsig zoo, thiab tsis pom muaj hematological lossis kev coj cwj pwm txawv txav. |
Haum rau nruab nrab - mus rau - siab - cov khoom noj qab haus huv txhua hnub thiab khoom noj txom ncauj. Kev thov ntawm kev txhawb nqa kev tiv thaiv thiab ua kom lub plab microbiota tau tso cai. Ceeb toom ntawm contraindication los yog tsawg heev npaum li cas yuav tsum tau. |
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IBD / Chronic Enteropathy hauv dev |
Kev pheej hmoo siab |
Txawm tias thaum lub sij hawm tshem tawm (CCECAI Tsawg dua los yog sib npaug rau 3), qhov koob tshuaj ntawm 9.13 mg / kg tuaj yeem ua rau mob hnyav thiab erythema. |
Beta-glucan poov xab hmoov yog pom zoo los tsim cov qauv hypoallergenic yam tsis muaj cov poov xab rho tawm, lossis ua kom nruj nruj ua ntej siv. |
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Cov dev nrog atopic dermatitis / osteoarthritis |
Muaj peev xwm thiab kev pheej hmoo ua ke. |
Raws li txoj cai, nws muaj cov tshuaj tiv thaiv -inflammatory zog. Txawm li cas los xij, hauv -cov xwm txheej hauv ntiaj teb no, kev tswj hwm qhov ncauj yuav ua rau cov tsos mob ntawm daim tawv nqaij ua rau cov dev muaj teeb meem IBD. |
Cov tshuaj pleev ib ce raug pom zoo rau kev tswj hwm qhov ncauj kom tsis txhob muaj kev pheej hmoo ntawm kev ua kom lub plab ntau dhau. |
Cov ntsiab lus
Hauv cov ntsiab lus, beta-glucan poov xab hmoov muaj kev nyab xeeb thiab muaj txiaj ntsig zoo rau kev noj zaub mov zoo rau feem coob ntawm cov dev. Txawm li cas los xij, qee cov dev uas muaj kab mob plab hnyuv loj (IBD nquag), paub txog keeb kwm ntawm kev ua xua, lossis rog rog nrog cov kab mob metabolic yuav tsum raug suav hais tias yog "muaj peev xwm siab heev- pab pawg muaj kev pheej hmoo."
Thaum txhim kho kev noj qab haus huv txhua hnub rau cov tsiaj nyeg, yuav tsum tau siv ntau npaum li cas, tsom rau kev tiv thaiv kab mob thiab kev tswj hwm plab microbiota. Kev koom tes nrog cov neeg muag khoom uas muaj peev xwm tshawb fawb muaj zog thiab kev tswj xyuas kev ua tau zoo ua kom paub meej cov khoom siv thiab ua raws li cov qauv purity rau cov khoom siv raw, txo cov saw hlau txaus ntshai. Los ntawm kev tsim qauv kev tshawb fawb nruj thiab kev pheej hmoo- kev tswj hwm- raws li kev sib txuas lus ntawm cov neeg siv khoom, beta-glucan poov xab hmoov yuav qhib kev lag luam ntau dua hauv kev lag luam khoom noj dev.
Kev sivs
[1] Amaral, AR, et al. Txhais Tib Neeg thiab Tsiaj Qauv Kev Kawm rau Dogs' thiab Cats' Veterinary Care: Beta-Glucans Application for Skin Disease, Osteoarthritis, and Inflammatory Bowel Disease Management. Microorganisms, 2024, 12(6), 1071.
[2] Marchi, PH, et al. Qhov cuam tshuam ntawm Kev nce qib ntawm Purified Beta-1,3/1,6-Glucans ntawm Fecal Microbiome, Digestibility, thiab Immunity Variables of Healthy Adult Dogs. Microorganisms, 2024, 12(1), 113.
[3] Kev Tsis Pom Zoo rau Poov xab Beta-Glucan ntxiv rau ob tus dev uas muaj kab mob plab hnyuv. PIB, 2026, 3(1), 7.
[4] Marchi, PH, et al. Kev ua xua rau Beta-Glucans nyob rau hauv ib tug dev rog: Cov ntaub ntawv ceeb toom ntawm kev lees paub thiab qhov tseeb. Phau ntawv Journal of Animal Physiology & Animal Nutrition, 2025, 1-6.
[5] Teb ntawm plab microbiome thiab metabolomic profiles rau POLYCAN, ib -glucan muab los ntawm Aureobasidium pullulans SM-2001 hauv beagles. Phau ntawv Journal of Animal Science thiab Biotechnology, 2026, 17, 63.
