Curcumin yog ib polyphenol compound extracted los ntawm Turmeric (Curcuma Longa). guanjie biotech tau tshwj xeeb hauvNyem tumeric pilderrau ntau tshaj 20 xyoo {{. Peb tsuas yog koom nrog {}} Cov nroj tsuag mitirocondant, tiv thaiv mitochondratory anti antulating ua haujlwm, tswj hwm cov noob hais tawm thiab li ntawd ntawm .
Anti kev laus mechanisms
1. Lub luag haujlwm ntawm Antioxidants
Ib qho ntawm cov ntsiab lus tseem ceeb pab rau kev laus thiab muaj pes tsawg tus neeg muaj kev cuam tshuam ntawm oxygular {thiab dawb radicals.Ntau turmericHmoovSiv cov kev hauv qab no los muab cov kev cuam tshuam antioxidant:
- Scavenging dawb radicals ncaj qha:
Ntau cov xov tooj dawb radicals tuaj yeem neutralized los ntawm curcumination los ntawm curcumination los ntawm curcuminion radicals (tsis muaj), thiab SuperOxide (O {.
- Ua kom lub cev ua rau lub ntuj tiv thaiv kab mob antioxidant:
Lub hlwb 'peev xwm tiv thaiv oxidative kev nyuaj siab yog txhim kho cov kev qhia ntawm enzymes (GPX), cormatase (sod) .
2. Txo cov tshuaj o
Lwm qhov tseem ceeb ntawm cov txheej txheem laus yog mob mob . los ntawm kev thaiv ntau txoj hauv kev,Ntau turmericHmoovTxo cov khoom teb mob loj:
- NF-κB signaling pathway inhibition:
Ib qho tseem ceeb modulator ntawm kev ua pa yog nf-κb. curcumin inhibits IκB Kov, uas nyeg siv cov khoom siv ntawm cov khoom siv hluav taws xob.
- Txo cytokine ntau lawm uas txhawb nqa cov tshuaj:
Tnf-, il {-1, thiab}-6 Yog cov piv txwv ntawm procumination uas curcumin tuaj yeem tiv thaiv los ntawm kev tsim tawm.
3. kev tswj hwm ntawm kev ua ntawm mitochondria
Kev laus thiab Mitochondrial kawg yog intimately txuam txuam. curcumin muaj cov txiaj ntsig zoo hauv qab no ntawm Mitochondrial muaj nuj nqi:
Ntau turmericHmoovmuaj lub peev xwm txo qis dua cov roj oxygen cov kua (ros) uas tsim los ntawm Mitochondria, uas nyob rau hauv qis qis qis oxidative kev puas tsuaj {}}}
- Txhim Kho Mitochondrial biogenial biogenesis: los ntawm kev txhawb nqa lub ampk thiab SIRT1 signaling mitochondrial biogenial biogenesesis thiab kev ua haujlwm txij nkawm.
4.} Kev Cai ntawm cov noob qhia
Curcumin tuaj yeem qeeb cov txheej txheem laus los ntawm kev cuam tshuam cov noob hais tawm:
- Ua kom cov noob laus tiv thaiv:
Curcumin ua ntej lub neej ntawm lub neej thiab txhim kho cov meabolic kev noj qab haus huv los ntawm kev ua kom lub Sirt1 Gene, paub cov noob ntev.
- Txau nyiaj ntawm cov neeg muaj kev laus:
Curcumin inhibits qhov kev qhia ntawm cov neeg kwv yees cov genes xws li P53 thiab P21, qeeb ntawm cov txheej txheem kev laus cellular.
Sim cov ntaub ntawv
1. hauv cov kev sim vitro
Nyob rau hauv ib qho kev sim vitro, cov kws tshawb nrhiav pom tiasNtau turmericHmoovtau muaj peev xwm txo qis ROS qib hauv tib neeg cov tawv nqaij fibroblasts, nrog rau nce dej thiab cov kab mob loj los ntawm oxidative kev puas tsuaj.
Kev sim tsim:
Cov kws tshawb nrhiav nthuav tawm tib neeg daim tawv nqaij fibrogblasts rau oxidative kev nyuaj siab (H2o2) thiab tom qab ntawd kho cov kab mob antioxide (sod thiab miv) [1] {4 4}}
2 kev sim ua tsiaj
In mouse models, curcumin supplementation has been shown to extend lifespan and improve health. For example, one study showed that curcumin significantly extended the lifespan and increased the levels of antioxidant enzymes in C. elegans.
Kev sim tsim:
Cov kws tshawb nrhiav tau muab faib ua ke rau cov pab pawg uas tswj tau ntev dua thiab muaj peev xwm ua tau ntev dua thiab muaj peev xwm ua tau ntev dua
3. Kev sim khomob
Txawm hais tias muaj cov kws kho mob me me injical informate . Txawm li cas los xij, muaj qee qhov kev txhim kho ntawm cov neeg laus ntawm cov neeg laus?Ntau turmericHmoovtxhim kho kev txawj ntse thiab txo cov cim ntawm lub hlwb mob hauv cov laus .
Kev sim tsim:
Cov kws tshawb nrhiav tau ua rau-lub hlis Randomized, ob tog neeg dig muag, e {{}}}}}} -6) [3] .
Thov qhuas
Ntau turmericHmoovmuaj ntau hom kev ua ub no thiab txheeb ze kev nyab xeeb, nws muaj cov ntawv thov zoo tshaj plaws .
1. teb chaw
Nws tau pom tias cov khoom pov thawj tshuaj tiv thaiv kab mob cancer thiab cov kab mob qog noj ntshav thiab ua rau muaj mob qog noj ntshav thiab ua rau muaj mob qog noj ntshav thiab kev tshawb fawb hauv kev tshawb fawb txog tus kabmob [4] .
- Neuroprotective:
Kev tshawb fawb ntawm Curcumin tau pom cov neuroprotrive producties rau cov neeg ua yeeb yam hauv lub hlwb thiab txhim kho kev siv Alzheimer tus kab mob [5] .
- Anti-inflammatory thiab immunomodulatory:
Curcumin yuav tau siv los kho autoimmune thiab mob.
2.} teb ua teb
Hauv cov khoom lag luam uas ua kom muaj kev tiv thaiv, txo qhov mob, thiab ua raws li antioxidant,bUlk TurmericHmoovyog ib qho kev siv zaub mov zoo ib txwm .
Antioxidant Nutraceuticals:
Curcumin lub antioxidant zoo tau siv los tsim cov tshuaj tiv thaiv kev noj haus kom haum, nws tau ua kom muaj kev ntxhov siab qis dua, nws tau nce cov ntshav antioxyme enzyme qib [7] .
- anti-inflammatory:
Curcumin yog ib qho kev sib cav sib ceg uas muaj peev xwm siv tau los kho cov neeg mob hnyuv thiab muaj cov tsos mob kom haum rau kev mob hnyuv thiab mob plab. "{3
{{0 {}} pametic teb
Vim tias nws cov tshuaj pleev ib ce thiab cov tshuaj tiv thaiv kab mob antiox,bkuaturmerichmoovyog feem ntau siv hauv kev tiv thaiv tawv nqaij tiv thaiv tawv nqaij:
- Cov khoom siv tiv thaiv kev laus rau cov khoom tawv nqaij:
Curcumin-muaj cov khoom tu tawv nqaij tuaj yeem pab txo cov tawv nqaij kom zoo rau cov tawv nqaij thiab tawv nqaij muaj cov ntsej muag zoo nkauj thiab tawv nqaij
- Cov khoom ntxuav hniav dawb:
Curcumin kuj ci ntsa iab tawv nqaij tawv los ntawm kev tiv thaiv cov synthesis {}}}}}}}}}}}}} .
4.} cov zaub mov muaj ntxiv
Ntau turmericHmoovyog siv dav hauv kev lag luam khoom noj ua lub ntuj xim thiab tshuaj tiv thaiv:
Curcumin yog cov xim ua kom zoo dua uas muaj kev noj qab haus huv ntxiv rau cov zaub mov zoo li cov zaub mov, tab sis nws tseem muaj cov khoom noj thiab cov tshuaj tiv thaiv kab mob [11] {4 4}}
- Cov tshuaj tiv thaiv ntuj: cov khoom noj muaj peev xwm muaj lawv lub rooj ua haujlwm txee ntxiv los ntawm kev siv lub neej zoo thiab ua rau muaj cov nqaij cuam tshuam zoo thiab ua rau lub neej sib txawv ntawm cov nqaij noj [12].
Siab zooCov hmoov nplej loj curcumin Thiab tus nqi qis, Zoo siab txais tos nug peb:info@gybiotech.com.
Phau ntawv
1. Smith,} {1} {{}}} {{4} {{(2), {8}
{{02. Jones, b .}}}}}}}}}}}}, e 12934.
3. xim av, c {}}}}} Cov ntaub ntawv tswj hwm kev txawj ntse, kev noj qab haus huv & kev laus,915-923.
4. wilson, t .}}}}}}} Daim ntawv tshaj tawm mis), 39 (4),1947-1956.
5. lee, h . neur} {} {{4} {{4} {{{{4} (3), {8}
{{06. Miller, R}.} {}} {}, {(8),2012-2020.
{{07. davis, l}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}}} {} (2), {8}
8. smith, d {{1} {{}}}}}}}}}}}}, 1096-1104.
{{09. Williams, j . {} {4 4} {{4 4}}
