Ceramidesyog cov chav kawm tseem ceeb ntawm lipid-zoo li molecules uas muaj dav nyob rau hauv tib neeg daim tawv nqaij thiab cell membranes. Hauv particular, lawv muaj cov haujlwm tseem ceeb hauv cov kab mob stratum corneum. Kev faib tawm ntawm ceramides yog complex thiab ntau yam. Lawv tuaj yeem muab faib ua ntau hom nyob ntawm lawv cov qauv tshuaj, kev ua haujlwm, thiab qhov chaw.
Lub hauv paus qauv ntawm ceramides
Lub hauv paus qauv ntawm ceramides muaj ob yam tseem ceeb.
- Sphingosine:
Sphingosine yog cov pob txha caj qaum ntawm ceramide thiab belongs rau cov saw ntev ntawm cov hauv paus. Sphingosine yog ib qho tseem ceeb ntawm cov amino cawv uas muaj cov kab hlau txuas nrog cov amino (-NH₂) thiab hydroxyl (-OH). Feem ntau sphingosine yog 18 carbon atoms ntev. Txawm li cas los xij, hauv qee qhov kev hloov pauv, cov kab txuas carbon ntev yuav txawv.
- Fatty acid sawb:
Qhov thib ob feem ntawm ceramide yog fatty acid. Nws txuas nrog cov amino pawg ntawm sphingosine ntawm amide daim ntawv cog lus (-NHCO-) los ua tiav cov ceramide molecule. Fatty acids yuav txawv ntawm qhov ntev, saturation, thiab branching txoj hauj lwm, ua rau ntau hom ceramides.
Tus qauv qauv yog raws li nram no:
R₁-CONH-CH₂-CH(OH)-CH₂-NH₂
Qhov twg sawv cev rau qhov ntev saw fatty acid feem. Thaum lub sphingosine ib feem muaj cov amino pawg thiab ob pawg hydroxyl ua haujlwm. Nws yog hydrophilic thiab hydrophobic thiab tuaj yeem ua lub luag haujlwm tseem ceeb hauv ob qho tib si aqueous thiab lipid ib puag ncig.
Kev faib tawm loj ntawm ceramides
Kev faib tawm ntawm ceramides feem ntau yog nyob ntawm lawv cov qauv tshuaj. Nws tuaj yeem raug cais raws li hom sphingosine, hom fatty acid, thiab lwm yam. Cov hauv qab no yog qee yam loj ntawm ceramides.
- Ceramide 1 (Ceramide EOS).
EOS hom ceramide yog hom ceramide uas muaj cov qauv tshwj xeeb uas tau tsim ntau txoj hauv kev los ntawm qhov tseeb tias nws feem ntau muaj kev sib txuas ntxiv ester (ester linkage) ntawm qhov kawg ntawm cov roj fatty acid. EOS-type ceramides yog siv dav hauv kev tiv thaiv kev laus thiab cov khoom tu tawv nqaij moisturizing los txhim kho cov tawv nqaij ua haujlwm thiab ua kom tawv nqaij ua kom ntev.
- Ceramide 2 (Ceramide NS).
Kuj hu ua Ceramide Type 1 (Ceramide 1), NS-type ceramides muaj fatty acid chains uas feem ntau saturated thiab feem ntau nyob ib ncig ntawm 24 carbons ntev. Hom ceramide no plays lub luag haujlwm tseem ceeb hauv daim tawv nqaij barrier, tshwj xeeb tshaj yog nyob rau hauv kev tswj ntawm daim tawv nqaij noo noo thiab tiv thaiv dej poob. ns ceramides tau siv dav hauv cov khoom tu tawv nqaij rau lawv lub peev xwm los txhim kho daim tawv nqaij moisturization.
- Ceramide 3 (Ceramide NP).
Ceramide 3 yog ib qho ceramide tsim los ntawm sphingosine thiab non-hydroxy fatty acids. Ceramide NP hmoov yog siv dav hauv cov khoom siv tawv nqaij. Guanjie Biotech tsim Ceramide 3 hmoov, uas muaj txiaj ntsig zoo rau cov tawv nqaij moisturizing thiab txhim kho daim tawv nqaij ua haujlwm.
- Ceramide 4 (Ceramide EOH).
Hom ceramide no feem ntau muaj cov kab sib txuas ntev dua nrog cov pab pawg ua haujlwm sib txawv. ceramide 4 ntxiv rau kev tiv thaiv thiab kho cov haujlwm ntawm daim tawv nqaij thiab feem ntau siv hauv cov khoom tu tawv nqaij qhuav heev.
- Ceramide 6 (Ceramide AP).
Ceramide 6 muaj qee qhov exfoliating zog. Nws pab slough tawm ntawm daim tawv nqaij laus thaum txhim kho daim tawv nqaij moisturizing muaj nuj nqi. Nws yog feem ntau siv los tiv thaiv kev laus thiab moisturizing khoom los txhim kho daim tawv nqaij zoo nkauj thiab radiance. Guanjie Biotech tsim Ceramide 6 hmoov. Cov sphingosine feem ntawm AP-type ceramide yog dihydrosphingosine, uas ua rau nws sib txawv ntawm cov qauv NS-type ceramides.
- Ceramide 9 (Ceramide EOP).
Cov ceramide no muaj cov roj fatty acid ntev thiab muaj ntau pawg ua haujlwm. Nws feem ntau pom muaj nyob rau hauv cov khoom tu tawv nqaij nrog kev tiv thaiv kev laus. Tsis tsuas yog ua ntau hom ceramides txawv hauv cov qauv, tab sis lawv txoj haujlwm hauv daim tawv nqaij kuj txawv. Cov molecules no ua hauj lwm ua ke los tsim cov tawv nqaij muaj zog tiv thaiv kab mob uas tiv thaiv daim tawv nqaij los ntawm ib puag ncig yam.
Ceramides tseem tuaj yeem raug cais raws li lawv qhov chaw, uas feem ntau suav nrog ceramides ntawm cov nroj tsuag keeb kwm, tsiaj keeb kwm thiab keeb kwm hluavtaws.
Ceramides ntawm tsob ntoo keeb kwm.
Feem ntau pom muaj nyob rau hauv cov nroj tsuag xws li nplej thiab nplej bran. Ceramides los ntawm cov nroj tsuag feem ntau yog siab nyob rau hauv polyunsaturated fatty acids thiab yog haum rau rhiab tawv nqaij, muab ib tug zoo moisturizing nyhuv tsis ua rau tawv nqaij khaus. Ceramides los ntawm cov nroj tsuag extracts feem ntau yog siv nyob rau hauv tej yam ntuj tso khoom tu tawv nqaij vim lawv tej yam ntuj tso.
Ceramides ntawm Tsiaj Keeb Kwm.
Ceramides ntawm tsiaj keeb kwm feem ntau yog muab rho tawm los ntawm cov ntaub so ntswg xws li bovine thiab porcine hlwb thiab yog nplua nuj nyob rau hauv lipids. Txawm hais tias lawv cov teebmeem zoo ib yam li cov ceramides hauv daim tawv nqaij, lawv tam sim no tsis tshua muaj siv hauv cov khoom siv tawv nqaij vim lawv txoj kev tshem tawm nyuaj thiab muaj peev xwm ua xua.
Synthetic Ceramides.
Raws li thev naus laus zis nce qib, hluavtaws ceramides tau dhau los ua qhov tseem ceeb. Ceramides uas tsim los ntawm cov tshuaj synthesis los yog bioengineering zoo ib yam li cov qauv rau ntuj ceramides. Txawm li cas los xij, cov qauv tuaj yeem ua kom zoo raws li qhov xav tau los txhim kho nws cov txiaj ntsig thiab txo cov kev mob tshwm sim. Synthetic ceramides yog cov ntshiab dua thiab tsis tshua muaj nqi los tsim cov khoom loj thiab tau siv dav hauv cov khoom tu tawv nqaij thiab tshuaj. Guanjie Biotech siv biogeneration los tsim Ceramide 3 thiab Ceramide 6.
Classification los ntawm Function
Raws li lawv cov haujlwm sib txawv, ceramides feem ntau tuaj yeem muab faib ua pawg hauv qab no.
- Moisturizing Ceramides.
Cov hom ceramides pom nyob rau hauv ntau yam khoom tu tawv nqaij yog tsim los txhim kho daim tawv nqaij muaj peev xwm moisturize. Piv txwv li, Ceramide 2 thiab Ceramide 3 yog cov tshuaj moisturizing ceramides uas kaw cov dej noo hauv daim tawv nqaij thiab tiv thaiv dej.
- Barrier Kho Ceramides.
Ceramides ua lub luag haujlwm tseem ceeb hauv kev kho cov tawv nqaij barrier. Tshwj xeeb tshaj yog nyob rau hauv kev saib xyuas ntawm cov tawv nqaij qhuav heev, puas tsuaj, Ceramide 1 thiab Ceramide 9 yog cov tshuaj kho cov ceramides uas pab kho cov tawv nqaij ua haujlwm tsis zoo.
- Anti-aging Ceramides.
Raws li peb muaj hnub nyoog, tus nqi ntawm ceramides hauv daim tawv nqaij txo qis, ua rau dryness, nplua kab thiab wrinkles. Nws muaj ceramides nrog anti-aging zog. Xws li Ceramide 6 thiab Ceramide 9 txhawb cov tawv nqaij rov ua dua tshiab, txo cov tawv nqaij thiab ua kom tawv nqaij elasticity.
Kev ua haujlwm thiab kev siv ntawm ceramides
Ceramide tsis tsuas yog ua lub luag haujlwm tseem ceeb hauv cov qauv ntawm cov kab mob lom, tab sis kuj koom nrog ntau yam txheej txheem physiological xws li xov tooj ntawm tes, kev loj hlob ntawm tes, thiab apoptosis. Hauv kev kho cov tawv nqaij kom zoo nkauj, moisturizing, tiv thaiv kev laus, thiab kho cov haujlwm ntawm ceramides tau txais kev saib xyuas thoob plaws. Cov ntawv thov tshwj xeeb suav nrog:
- Daim tawv nqaij moisturization:
Ceramides tuaj yeem kaw cov dej noo thiab txo cov dej los ntawm kev tsim cov qauv bilayer hauv daim tawv nqaij stratum corneum.
- Anti-aging:
Ceramides ua lub luag haujlwm tseem ceeb hauv kev txhawb nqa cell rov tsim dua tshiab thiab kho thiab tuaj yeem pab qeeb cov txheej txheem kev laus ntawm daim tawv nqaij.
- Kho daim tawv nqaij Barrier:
Guanjie Biotech yog cov khoom lag luam ceramides. Peb tsim cov ceramides 3 thiab ceramide 6. Cov khoom yog dawb rau cov hmoov dawb dawb nrog ntau dua los yog sib npaug rau 95% purity. Peb siv cov txheej txheem fermentation los tsim cov ceramides zoo. Peb tuaj yeem muab cov qauv ceramide 3 thiab ceramide 6. Txais tos nuginfo@gybiotech.com.
