Oat Beta Glucan Ua Li Cas Rau Cov tawv nqaij?

Oat beta-glucan hmoovyog lub siab -molecular- hnyav polysaccharide muab los ntawm oats (Avena sativa). Nws tus nqi hauv kev tu tawv nqaij tau lees paub dav dav. Beta-glucan oat hmoov ua tau ntau dua li muab cov dej noo yooj yim thiab thickening zog. Oat beta-glucan khi rau cov receptors tshwj xeeb ntawm cov tawv nqaij tiv thaiv kab mob thiab fibroblasts. Nws tuaj yeem txhawb kev kho daim tawv nqaij, muab kev tiv thaiv - yees duab cuam tshuam, thiab txhim kho kev tiv thaiv kab mob. Kev nce qib hauv molecular hnyav tswj thev naus laus zis thiab cov txheej txheem fermentation extraction tau nthuav dav nws cov ntawv thov. Tshwj xeeb, kev txhim kho ntawm qis-molecular- hnyav oat beta{13}}glucan tau tsim cov hauv kev tshiab. Nws qhia tau hais tias muaj peev xwm muaj peev xwm nyob rau hauv kev nkag mus rau hauv transdermal thiab kev tswj cov hom phiaj.

Oat Beta -Glucan yog dab tsi?

Oat beta -glucan yog ib qho tsis yog - starch polysaccharide. Nws muaj nyob rau hauv lub cell phab ntsa ntawm oat endosperm thiab aleurone txheej. Nws cov qauv tshuaj yog tsim los ntawm D-glucose monomers. Cov monomers no txuas los ntawm -(1,3) thiab -(1,4) glycosidic bonds. Cov qauv no txiav txim siab txog nws lub cev, xws li dej siab - tuav lub peev xwm thiab gelling peev xwm. Beta-glucan oat hmoov kuj txiav txim siab nws txoj haujlwm lom neeg.

 

 

Physicochemical Properties

Nyob rau hauv cov tshuaj pleev ib ce, beta-glucan oat hmoov feem ntau tshwm raws li ib tug dawb mus tawm- dawb hmoov. Nws yog dej -soluble. Nws muaj ntau pawg hydroxyl hauv nws cov saw hlau molecular. Vim li no, nws muaj zog hydrogen bonding peev xwm. Qhov no ua rau nws muaj txiaj ntsig zoo moisturizing thiab zaj duab xis- ua tus neeg sawv cev. Nws tuaj yeem tsim ib zaj duab xis breathable ntawm daim tawv nqaij. Qhov no yuav pab txo cov dej noo.

 

 

Qhov cuam tshuam ntawm Molecular Luj ntawm Kev Ua Haujlwm

Molecular hnyav yog qhov tseem ceeb uas cuam tshuam rau kev ua haujlwm ntawm daim tawv nqaij. Siab molecular hnyav oat beta-glucan tuaj yeem tsim cov yeeb yaj kiab tiv thaiv zoo. Nws tseem muab cov nyhuv moisturizing tam sim ntawd. Txawm li cas los xij, nws qhov loj me me me ua rau nws nyuaj rau nkag mus rau stratum corneum. Nws feem ntau ua rau ntawm daim tawv nqaij.

Cov kev tshawb fawb tsis ntev los no qhia tau hais tias qhov hnyav molecular oat beta -glucan (ib puag ncig 1 kDa) muaj qhov zoo dua solubility. Nws kuj qhia tau hais tias cov tawv nqaij permeability zoo dua. Cov molecules me me no yog tsim los ntawm enzymatic hydrolysis. Lawv tuaj yeem dhau los ntawm qhov chaw intercellular. Lawv tuaj yeem ncav cuag cov khaubncaws sab nraud povtseg ntawm cov epidermis thiab txawm tias lub dermis. Lawv tuaj yeem cuam tshuam nrog fibroblasts.

 

Oat Beta yog dab tsi -Glucan Ua rau Daim tawv nqaij?

Beta-glucan oat hmoov ua tau ntau dua li muab lub cev moisturization. Nws tuaj yeem khi rau cov receptors tshwj xeeb ntawm cov tawv nqaij, xws li Dectin-1 receptors. Qhov no activates teeb liab txoj kev. Oat beta-glucan rau daim tawv nqaij tuaj yeem pab tswj cytokine secretion.

Daim tawv nqaij Barrier Kho Mechanisms

Kev ncaj ncees ntawm daim tawv nqaij barrier nyob ntawm qhov sib npaug ntawm keratinocyte proliferation thiab sib txawv. Beta-glucan oat hmoov tuaj yeem khi rau Dectin-1 receptor nyob rau hauv epidermis. Cov txheej txheem no ua rau ERK thiab p38 teeb liab txoj hauv kev. Nws kuj ua rau kom cov lus qhia ntawm calcium-sensitive receptors.

Thaum daim tawv nqaij barrier puas lawm, calcium concentration gradient nyob rau hauv lub epidermis ploj. Qhov kev hloov no tuaj yeem cuam tshuam kev sib txawv ntawm keratinocyte. Ua kom calcium ntxiv-rhiab receptor qhia ua rau keratinocytes teb rau cov calcium ions extracellular. Raws li qhov tshwm sim, kev sib txawv ib txwm tuaj yeem txuas ntxiv txawm tias nyob hauv calcium- tsis txaus.

Cov kev tshawb fawb tau pom tias cov txheej txheem no tuaj yeem txo qis epidermal hyperplasia thiab ua kom muaj kev kho qhov thaiv. Ib txoj kev tshawb fawb xyoo 2024 kuj pom tau tias oat -glucan tuaj yeem ua rau muaj kev sib txuas ntawm cov protein ntau thiab txhawb lipid synthesis hauv stratum corneum.

Yog li ntawd, oat beta-glucan tuaj yeem siv los ua cov khoom muaj nyob hauv cov khoom tu tawv nqaij rau kev kho cov tawv nqaij rhiab heev, tom qab- txheej txheem kev saib xyuas, thiab kho cov tawv nqaij barrier. Nws cov mechanism ntawm kev txiav txim yog txhais tau zoo. Nws txoj kev kho mob kuj yog qhov tseeb. Qhov no muab kev txhawb nqa kev tshawb fawb txhim khu kev qha rau kev tsim khoom.

Anti- yees duab thiab kev tiv thaiv DNA

Ultraviolet (UV) hluav taws xob yog qhov ua rau muaj kev cuam tshuam loj ntawm cov duab thiab cov tawv nqaij puas. UVB irradiation induces fibroblasts los tsim reactive oxygen hom (ROS). Cov txheej txheem no ua rau apoptosis thiab inflammatory teb.

Kev tshawb fawb tau lees paub tias oat beta -glucan thiab nws cov oligosaccharide derivatives tuaj yeem tswj cov txheej txheem lom neeg muaj feem cuam tshuam nrog photodamage. Cov kev tshawb fawb tau pom tias beta-glucan oat hmoov tuaj yeem tswj cov kev qhia ntawm cov noob xws li VEGFA (angiogenesis), LGALS-3 (aging), thiab CDK1 (apoptosis). Hauv UVB-induced mob tawv nqaij qauv, oat beta-glucan txo oxidative kev nyuaj siab. Nws kuj tseem txo qis ROS theem ntawm intracellular thiab inhibited qhov tso tawm ntawm inflammatory yam. Yog li ntawd, nws txhawb kev kho cov tawv nqaij photodamaged.

Tsis tas li ntawd, bioactive compounds hauv oats, xws li avenanthramides, muaj cov qauv sib txawv ntawm -glucan. Txawm li cas los xij, thaum ua ke nrog -glucan, lawv qhia cov tshuaj tiv thaiv antioxidant thiab tiv thaiv - cov teebmeem inflammatory.

Immunomodulation thiab Anti- mob

Cov tawv nqaij rhiab heev feem ntau tshwm sim los ntawm kev ua haujlwm tsis zoo ntawm daim tawv nqaij thiab cov lus teb tsis zoo neurosensory. Beta-glucan oat hmoov muaj immunomodulatory zog. Nws tuaj yeem tswj cov kev tso tawm ntawm cov tshuaj tiv thaiv kab mob xws li interleukins, interferons, thiab chemokines.

Cov kev tshawb fawb tsiaj tau pom tias -glucan tuaj yeem txo cov tawv nqaij o thiab txhim kho cov tsos mob ntawm atopic dermatitis qauv. Hauv cov khoom siv tshuaj pleev ib ce tsim los tiv thaiv - ua xua thiab soothing lub hom phiaj, oat -glucan tuaj yeem pab txo qhov mob thiab txo qhov mob erythema thiab stinging. Nyob rau tib lub sijhawm, nws tuaj yeem ntxiv dag zog rau daim tawv nqaij los ntawm kev tswj xyuas kev ncaj ncees ntawm stratum corneum.

Daim ntawv thov muaj peev xwm nyob rau hauv daim tawv nqaij xa khoom

Ntxiv rau qhov ua cov khoom xyaw nquag, beta-glucan oat hmoov kuj tuaj yeem ua haujlwm ua tus xa khoom xa tuaj. Cov cheeb tsam tshwj xeeb ntawm nws cov qauv molecular muaj cov khoom amphiphilic. Hloov kho oat beta-glucan tuaj yeem ua ke nrog lactoferrin thiab lwm cov tshuaj sib xyaw ua ke los tsim cov txheej txheem xa tawm pob tshab rau hydrophobic polyphenols xws li curcumin.

Txoj hauv kev no yuav pab daws cov teeb meem ntawm cov dej tsis zoo thiab kev tawg ntawm cov khoom xyaw hydrophobic hauv dej-raws li cov tshuab ua kom zoo nkauj. Rau cov neeg tsim khoom, oat beta -glucan yog ntau dua li cov khoom xyaw nquag. Nws kuj yog ib qho ntsuab thiab ib txwm muab tau los ntawm transdermal tus neeg nqa khoom.

Dab tsiYogOat Beta GlucanSiv rau hauvdaim tawv nqaijTeb?

Indications thiab Product Positioning

Raws li cov txheej txheem saum toj no, beta-glucan oat hmoov yog tsim rau cov nram qab no kawg- pawg khoom:

• Anti-aging thiab wrinkle-txo cov khoom: Nws txhawb collagen synthesis. Nws pab txo cov kab zoo thiab cov tawv nqaij laxity.

• Tshaj tawm- cov khoom kho hnub ci thiab kev tiv thaiv: Beta-glucan oat hmoov muab cov teebmeem antioxidant thiab txhawb kev kho DNA puas. Nws tuaj yeem siv rau hauv cov tshuaj pleev thaiv hnub niaj hnub ua cov khoom siv kho ntxiv. Nws kuj tseem tsim nyog rau kev tshaj tawm - tshuaj pleev thaiv hnub.

• Cov tawv nqaij rhiab heev thiab teeb meem- kho cov khoom: Nws txhawb kev tiv thaiv kab mob thiab kho qhov txhab. Nws yog haum rau rosacea, tshuaj hormone- ntsig txog dermatitis, thiab tawv nqaij rhiab lossis tsis yooj yim.

• High-kawg moisturizing cov khoom thiab cov ntshav: Tsawg molecular hnyav beta-glucan txhim kho cov tawv nqaij nkag mus. Oat beta-glucan hmoov txhawb kev sib sib zog nqus dej thiab txhim kho kev nqus ntawm cov khoom xyaw tom ntej.

Kev txiav txim siab txog kev xaiv raw khoom

Thaum xaiv oat beta-glucan raw cov ntaub ntawv, molecular phaus faib yog qhov tseem ceeb tsis zoo.

• High molecular weight (>200 kDa): Beta-glucan oat hmoov feem ntau nyob ntawm daim tawv nqaij. Nws tsim cov yeeb yaj kiab tiv thaiv thiab muab dej tam sim ntawd. Nws muaj qhov viscous ntau dua. Nws yog haum rau zaj duab xis- tsim thiab occlusive khoom xws li pw lub qhov ncauj qhov ntswg thiab moisturizing cream.

• Tsawg molecular hnyav (<10 kDa, especially β-GOS around 1 kDa): It has better skin penetration. It can reach the epidermal-dermal junction. It supports biological repair functions. It is suitable for functional products such as serums, freeze-dried powders, and ampoules.

Raws li bulk beta-glucan oat hmoov tsum, Guanjie Biotech muab bulk betaglucare hmoov raw cov ntaub ntawv nrog ruaj khov molecular hnyav tswj tshuab thiab nruj zoo soj ntsuam. Qhov no ua kom muaj kev ua haujlwm zoo ib yam hauv kev siv tshuaj pleev ib ce.

Compatibility thiab Stability

Beta-glucan oat hmoov qhia tau hais tias muaj txiaj ntsig zoo. Nws muaj qhov ua kom sov zoo. Nws tuaj yeem yaj hauv cov dej hauv dej siab tshaj 70 degree. Nws qhov ruaj khov feem ntau yog qhov zoo hauv pH ntawm 5-8. Nws ua tau zoo nyob rau hauv nruab nrab thiab me ntsis acidic skincare systems.

Nws yog sib xws nrog ntau moisturizing thiab kho cov khoom xyaw xws li polyols, hyaluronic acid, thiab Centella asiatica extract. Txawm li cas los xij, hauv cov txheej txheem muaj zog acidic (xws li siab -kev sib xyaw AHA), muaj zog alkaline systems, lossis siab - electrolyte formulations, kev ruaj ntseg ua ntej thiab kev kuaj viscosity yuav tsum tau.

Xaus:

Oat beta-glucan yog ib qho kev tshawb fawb pom tau tias muaj ntau yam khoom siv tshuaj pleev ib ce. Nws tsis tsuas yog muaj cov haujlwm yooj yim moisturizing thiab thickening, tab sis kuj ua tiav cov tawv nqaij sib sib zog nqus kho thiab tiv thaiv - kev tiv thaiv kev yees duab los ntawm cov txheej txheem lom neeg xws li tswj cov haujlwm fibroblast, inhibiting oxidative stress, thiab modulating kev tiv thaiv kab mob.

Raws li cov neeg siv khoom tau nkag siab tob txog kev saib xyuas tawv nqaij thiab qis -molecular- hnyav betaglucare oat hmoov transdermal technology matures, daim ntawv thov ntawm cov khoom xyaw no hauv cov khoom siv tu tawv nqaij yuav nce ntxiv. Rau cov hom tshuaj pleev ib ce thiab cov tuam txhab tsim khoom, xaiv qhov loj - nplai beta-glucan oat hmoov cov chaw muag khoom nrog kev tswj xyuas zoo thiab muaj peev xwm muab tau ruaj khov, xws li Guanjie Biotech, yog qhov lav rau kev ruaj ntseg hauv kev lag luam sib tw.

Cov ntaub ntawv:

[1] Kawm txog kev saib xyuas ntawm daim tawv nqaij ntawm oat -glucan rho tawm los ntawm ob- txoj kev fermentation. Kev Lag Luam Tshuaj Txhua Hnub, 2021.

[2] Oat -Glucooligosaccharides: Kev npaj, kev ua yam ntxwv, daim tawv nqaij permeability, thiab kho photodamage. Kev Tshawb Fawb Carbohydrate, 2025.

[3] Oat Cosmetics Debuts Rejuvaveen, Active Skin Care Ingredient. Cosmetics & Toiletries, 2023.

[4] Kev siv ntawm -glucan hauv tshuaj pleev ib ce. Fragrance and Cosmetics, 2007.

[5] Ntau Antioxidative thiab Bioactive Molecules ntawm Oats hauv Tib Neeg Kev Noj Qab Haus Huv. Khoom noj khoom haus, 2021.