Diindolylmethane (DIM) yog ib qho tshuaj lom neeg lom neeg tsim hauv tib neeg lub cev tom qab kev zom ntawm qee cov nroj tsuag phytochemicals pom hauv cov zaub cruciferous. Qhov tseem ceeb, zaub tsis muaj qhov tseem ceeb ntawm pre- tsim DIM. Hloov chaw, lawv muaj cov khoom ua ntej hu ua indole-3-carbinol (I3C), uas tau hloov mus rau hauv DIM hauv acidic ib puag ncig ntawm lub plab. Thiab cov zaub twg muaj Diindolylmethane?
Cov zaub twg muaj Diindolylmethane?
Cov zaub uas ua rau DIM tsim muaj rau tsev neeg Brassicaceae (Cruciferae). Cov nroj tsuag no yog tus cwj pwm los ntawm qib siab ntawm glucosinolates - sulfur- muaj phytochemicals lub luag hauj lwm rau lawv cov aroma thiab kev noj qab haus huv - txhawb zog. Hauv qab no yog cov zaub tseem ceeb cuam tshuam nrog kev tsim DIM.
Broccoli
Broccoli muaj cov qib siab ntawm glucobrassicin, ib qho tshwj xeeb glucosinolate uas hloov mus rau indole-3-carbinol (I3C) thaum cov ntaub so ntswg puas (txiav, zom, sib tov). I3C tom qab ntawd nkag mus rau acid-catalyzed condensation hauv plab kom tsim DIM.
• Kwv yees li 20–60 mg DIM precursors ib 100 g tshiab broccoli
• Broccoli sprouts tej zaum yuav muaj 10–50 npaug ntau dua precursor theem dua broccoli paub tab.
Cov concentration siab yog los ntawm glucobrassicin thiab lwm cov tshuaj bioactive, uas hloov mus rau I3C thiab tom qab ntawd mus rau DIM hauv plab.
Brussels Sprouts
Brussels sprouts yog cov khoom noj muaj txiaj ntsig zoo tshaj plaws ntawm glucobrassicin. Thaum noj, enzymatic hydrolysis hloov glucobrassicin rau hauv I3C, uas tom qab ntawd tsim DIM.
• Kwv yees li 30–80 mg muaj peev xwm DIM ib 100 g (tom qab kev zom zaub mov hloov dua siab tshiab)
Lawv paub tshwj xeeb tshaj yog rau kev cuam tshuam cov tshuaj estrogen vim yog lawv cov indole ntom ntom.
Zaub qhwv
Ob qho tib si ntsuab thiab liab zaub muab ntsuas tau qib ntawm glucobrassicin, ib qho precursor uas tuaj yeem hloov mus rau hauv diindolylmethane (DIM) thaum lub sijhawm zom zaub mov. Cov txheej txheem fermentation, xws li cov siv los ua sauerkraut, tuaj yeem hloov cov ntsiab lus ntawm glucosinolate nyob ntawm kev ua haujlwm ntawm microbial thiab kev ua haujlwm, tab sis cov zaub nyoos tshiab tseem yog cov khoom noj muaj txiaj ntsig zoo. Kwv yees DIM precursor tawm los yog kwv yees li 10-35 mg rau 100 g ntawm zaub qhwv tshiab.
Kale
Kale yog ib qho khoom noj khoom haus -dense cruciferous zaub nplua nuj nyob rau hauv glucosinolates, tshwj xeeb tshaj yog glucobrassicin. Thaum cov nplooj raug txiav los yog zom, cov enzyme myrosinase hloov cov tshuaj no mus rau hauv indole -3-carbinol, uas tuaj yeem tsim ntxiv diindolylmethane (DIM) hauv plab. Kale lub iab me ntsis, pungent tsw qhia nws cov sulfur-muaj phytochemicals. Nws feem ntau muab txog 25-60 mg DIM precursor sib npaug ib 100 g.
Cauliflower
Cauliflower muaj cov qib qis ntawm glucobrassicin, muab kwv yees li 8-25 mg DIM precursor sib npaug rau 100 g. Txawm hais tias nws cov concentration qis dua broccoli los yog Brussels sprouts, kev noj ib txwm muaj peev xwm tseem tuaj yeem ua rau diindolylmethane (DIM) tsim tom qab zom mov los ntawm kev hloov pauv ntawm indole tebchaw hauv plab.
Pob choy (pak choi)DIINDOLYLMETHANE
Bok choy (pak choi) yog cov zaub cruciferous nplua nuj nyob hauv indole glucosinolates uas tuaj yeem hloov mus rau hauv diindolylmethane (DIM) tom qab zom zaub mov. Nws yog dav siv nyob rau hauv Asian cuisines thiab muab kwv yees li 8-20 mg DIM sib npaug ib 100 g. Kev ua noj ua haus maj mam, xws li lub teeb steaming lossis ceev do-frying, pab khaws cov ntsiab lus ntawm glucosinolate zoo dua li lub sijhawm boiling, uas yuav ua rau cov zaub mov poob.
Turnips
Turnips thiab lawv cov nplooj saum toj ob leeg muab glucobrassicin, qhov tseem ceeb precursor rau DIM tsim. Cov zaub ntsuab feem ntau muaj cov concentration ntawm phytochemicals ntau dua li hauv paus nws tus kheej. Cov qib kwv yees li 5-15 mg rau 100 g rau hauv paus thiab 15-40 mg rau 100 g rau zaub, ua rau cov nplooj tshwj xeeb muaj txiaj ntsig zoo.
Mustard zaub ntsuab
Mustard zaub ntsuab paub txog lawv cov ntse, pungent tsw, uas tshwm sim los ntawm glucosinolate cov khoom tawg. Lawv muaj ob qho tib si aliphatic thiab indole glucosinolates, suav nrog glucobrassicin, thiab muab kwv yees li 20-50 mg DIM sib npaug hauv 100 g, muab tso rau hauv cov khoom noj khoom haus nplua nuj.
Collard zaub ntsuab
Collard zaub ntsuab yog cov khoom noj khoom haus-cov nplooj tuab tuab uas xa cov indole-3-carbinol (I3C) precursors thaum lub sij hawm zom mov, ua rau DIM tsim. Feem ntau ntawm 20-45 mg rau 100 g, nyob ntawm ntau yam thiab loj hlob.
Arugula (zeeg)DIINDOLYLMETHANE
Arugula ( foob pob hluav taws) belongs rau tib tsev neeg botanical tab sis feem ntau muaj qis dua ntawm indole glucosinolates piv nrog broccoli - hom zaub. Nws tseem txhawb nqa DIM ntau lawm, nrog kwv yees li 5-15 mg rau 100 g.
Yog vim li cas cov zaub no tsim DIM?
Cruciferous zaub yog txuam nrog diindolylmethane (DIM) ntau lawm vim hais tias lawv muaj cov sulfur tshwj xeeb -muaj phytochemicals hu ua glucosinolates, tshwj xeeb yog glucobrassicin. Kev tsim ntawm DIM los ntawm cov zaub no tshwm sim los ntawm ntau yam -kab biochemical txoj hauv kev cuam tshuam nrog cov enzymes cog thiab tib neeg lub plab zom mov.
• Muaj Glucobrassicin
Ua ntej, cov nroj tsuag tsis zoo ib txwm khaws glucobrassicin cais los ntawm kev ua kom muaj enzyme hu ua myrosinase. Qhov kev sib cais no txwv tsis pub muaj tshuaj lom neeg tshwm sim ua ntej cov ntaub so ntswg puas. Thaum cov zaub raug txiav, crushed, los yog chewed, cellular qauv tawg, cia myrosinase tuaj rau hauv kev sib cuag nrog glucobrassicin. Cov enzyme tom qab ntawd hydrolyzes glucobrassicin rau hauv indole-3-carbinol (I3C), uas yog cov khoom noj khoom haus tam sim ntawm DIM.
• Enzymatic hloov dua siab tshiab thaum noj
Thib ob, tom qab noj, I3C nkag mus rau hauv lub plab, qhov chaw uas muaj kua qaub (feem ntau pH 1-3) txhawb kev sib xyaw ua ke. Thaum lub sij hawm tus txheej txheem no, ntau yam I3C molecules ua ke los ua ib tug ob peb biologically active tebchaw, nrog diindolylmethane yog cov feem ntau kawm thiab physiologically cov khoom. Cov kua qaub no -catalyzed hloov dua siab tshiab yog thawj qhov laj thawj DIM nws tus kheej tsis muaj nyob hauv cov zaub nyoos.
• Kev hloov pauv plab acid
Thaum kawg, vim tias DIM tsim nyob ntawm kev zom zaub mov, yam xws li kev ua noj ua haus, lub plab acidity, thiab tus neeg lub plab microbiota tuaj yeem cuam tshuam tus nqi ntawm DIM thaum kawg tsim thiab nqus tau. Hauv cov ntsiab lus, cov zaub no tsim DIM ncaj qha los ntawm kev muab cov glucobrassicin, uas ua rau muaj kev hloov pauv enzymatic thaum lub plab zom mov.
Yog vim li cas tsuas yog CruciferousZaub?
Diindolylmethane (DIM) yog tsim los ntawm cov zaub cruciferous vim lawv muaj indole glucosinolates, tshwj xeeb tshaj yog glucobrassicin, uas yog cov yam ntxwv ntawm cov tsev neeg Brassicaceae cog. Thaum cov zaub no raug txiav los yog zom, glucobrassicin hloov mus rau hauv indole-3-carbinol thiab tom qab ntawd mus rau hauv DIM hauv acidic ib puag ncig ntawm lub plab. Feem ntau lwm cov zaub, suav nrog carrots, txiv lws suav, thiab spinach, tsis muaj cov ntsiab lus ntawm cov precursors, yog li lawv tsis tuaj yeem tsim DIM thaum lub sijhawm zom zaub mov.
Cov ntsiab lus
Cov zaub uas cuam tshuam nrog DIM ntau lawm suav nrog zaub paj, brussels sprouts, cabbage, kale, cauliflower, bok choy, turnips, mustard zaub, collard zaub, thiab arugula. Cov zaub no tsis muaj qhov tseem ceeb ua ntej - tsim DIM. Hloov chaw, lawv muab glucobrassicin, uas hloov mus rau indole-3-carbinol thiab tom qab ntawd mus rau diindolylmethane hauv plab. Kwv yees DIM cov ntsiab lus ua ntej ntawm 5 mg mus rau 80 mg rau 100 g, nyob ntawm seb hom zaub, kev npaj, thiab kev loj hlob.
Koj tuaj yeem noj cov zaub no kom tau txais cov ntshiab diindolylmethane thiab qee cov tshuaj diindolylmethane. Guanjie Biotech yog ib qho khoom lag luam diindolylmethane hmoov. Peb siv cov tshuaj synthesis los tsim nws. Peb muab siab - zoo Diindolylmethane hmoov. Txais tos kom nug nrog peb ntawminfo@gybiotech.com.
Cov ntaub ntawv:
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[2] Verhoeven, DT, Verhagen, H., Goldbohm, RA, van den Brandt, PA, & van Poppel, G. (1997). Kev tshawb fawb txog kab mob ntawm Brassica zaub thiab kev pheej hmoo mob qog noj ntshav. Cancer Epidemiology, Biomarkers & Tiv Thaiv, 6(9), 733–748.
[3] Jeffery, EH, & Araya, M. (2009). Physiological teebmeem ntawm cruciferous glucosinolates. Phytochemistry Reviews, 8, 283–298. doi: 10.1007/s11101-009-9127-5
[4] Conaway, CC, Zhang, Y., & Dashwood, RH (2002). Indole-3-carbinol thiab diindolylmethane: Chemistry, metabolism, thiab tiv thaiv qog noj ntshav. Mutation Research, 555(1–2), 191–202.
[5] Kassie, F., Parzefall, W., & Knasmüller, S. (2007). Chemopreventive teebmeem ntawm indole-3-carbinol thiab nws cov derivatives. Toxicology thiab Applied Pharmacology, 224(3), 326–334.
[6] Traka, M., & Mithen, R. (2009). Glucosinolates, isothiocyanates thiab indoles hauv Brassica zaub: txoj hauv kev biochemical thiab kev noj qab haus huv. Phytochemistry Reviews, 8(1), 1–15.
