Ceramide Powder Bulk

Ceramide Powder Supplier:

Guanjie tshwj xeeb hauvceramide hmoov ntaunrog 20 xyoo dhau los hauv kev lag luam no. Cov khoom yog cov hmoov dawb rau cov hmoov dawb uas tsis muaj ntxhiab tsw. Peb sim nws siv HPLC thiab qhov kev ntsuam xyuas ntawm nws tsawg kawg yog 95%. Tus kheej cov kab ntau lawm thiab cov chaw ua haujlwm ywj pheej, uas tswj hwm kev tswj hwm zoo thoob plaws hauv cov txheej txheem tsim khoom. Qhov no ua kom ntseeg tau tias cov ceramide koj tau txais yog tus qauv siab tshaj plaws.

 

Vim li cas thiaj xaiv Guanjie?

● Ob lub chaw ua haujlwm ywj pheej thiab peb txoj kab ntau lawm.

● Pab neeg tshawb fawb kev tshaj lij thiab muaj cov chaw sim.

● Muab qhov kev kuaj thib peb.

● Muaj kev sib koom tes muaj zog: Northwestern University thiab Suav Academy ntawm Sciences chaw tshawb fawb.

 

COA:

Ceramide 3

Yam khoom		SPECIFICATIONS	TSEEM CEEB
Qhov tshwm sim		Dawb rau tawm - Dawb hmoov	Ua raws
tsw		Tsis hnov ​​tsw	Ua raws
Kev ntsuam xyuas (HPLC)		Ntau dua lossis sib npaug li 95%	96.9%
Melting point		98-108 degree	Ua raws
Poob ntawm ziab		Tsawg dua lossis sib npaug rau 2.0%	Ua raws
Residue ntawm ignition		Tsawg dua los yog sib npaug rau 0.5%	Ua raws
Total Heavy metals		Tsawg dua lossis sib npaug li 10ppm	Ua raws
Pb		Tsawg dua lossis sib npaug rau 3.0ppm	Ua raws
Raws li		Tsawg dua los yog sib npaug rau 1.0ppm	Ua raws
Cd		Tsawg dua los yog sib npaug rau 1.0ppm	Ua raws
Hg		Tsawg dua lossis sib npaug rau 0.1ppm	Ua raws
Residual kuab tshuaj: Methol		Tsawg dua lossis sib npaug li 3000ppm	Ua raws
Kev kuaj microbial
Tag nrho cov kab mob aerobic	Tsawg dua lossis sib npaug li 500 cfu / g		Ua raws
Poov thiab Moulds, CFU / ml	Tsawg dua lossis sib npaug li 100cfu / g		Ua raws
E. Coli	Tsawg dua lossis sib npaug li 30 MPN / 100g		Ua raws
Salmonella	Tsis zoo		Tsis zoo
Staphylococcus aureus	Tsis zoo		Tsis zoo
Cia: Sealed, lightless, txias thiab ventilated qhov chaw rau preservation
Txee lub neej: Ib xyoos thaum khaws cia zoo.
Xaus: ua raws li cov qauv kev lag luam

 

Ceramide yog dab tsi?
3 Ceramide yog lub pob txha hydrophobic ntawm sphingolipids. Sphingolipids yog ib qho ntawm cov lipid tseem ceeb ntawm cov cell membranes. Ceramides yog lipids uas muaj sphingosine thiab fatty acids covalently txuas los ntawm amide bonds. Twb muaj raws li cov fatty acids uas sib txawv C14-C26 saw lengths, lawv yog cov hydrophobic heev.

 

Cov ntaub ntawv txhaj tshuaj

Qauv: Amide-AP-stearate-YL Qauv: ID Amide-AP-stearate-YL

Txhaj ntim: 10 (μL) Channel Lub Npe: Amide-ap-stearate -YL -(BOX- Channel 1

Txoj kev tsom xam: YL5001-01-07-25min Operator: Admin

Hnub tim: 2023-02-23 23: 56:49

 

 

PEAK LIST

Tsis muaj	Lub npe	Lub sijhawm khaws cia (min)	Peak cheeb tsam (mV*s)	Peak dav (min)	Ib nrab-peak dav (min)	Peak qhov siab (mV)	Thaj tsam feem pua (%)	Peak-type
1	N.A.	11.623	14692.455	0.208	0.134	1744.475	96.970	BB
2	N.A.	12.138	459.088	0.140	0.084	83.427	3.030	BB
3	Tag nrho

 

Ceramide Synthesis

Muaj peb txoj hauv kev tseem ceeb uas cov ceramides raug tsim tawm hauv lub cev: ab initio synthesis, sphingomyelin hydrolysis, thiab txoj kev rov ua dua tshiab.

 

● Ab initio synthesis ntawm ceramide

Ab initio synthesis yog tus yam ntxwv tshaj plaws ntawm peb txoj kev sib txuas ntawm ceramide. Txoj kev pib nrog kev sib xyaw ntawm L-serine thiab palmitoyl CoA los ntawm serine phosphoribosyltransferase (SPT) los tsim 3-keto sphingomyelin. Qhov no ces txo mus rau sphingosine los ntawm 3-ketosphingosine reductase. Tom qab acylation ntawm sphingosine rau dihydroceramide los ntawm sphingosine N-acyltransferase. Kev txo qis tom qab ntawm dihydroceramide rau ceramide los ntawm dihydroceramide desaturase (Des1 thiab -2).

 

● Hydrolysis ntawm sphingomyelin

Txoj kev thib ob ntawm kev tsim cov ceramide yog hydrolysis ntawm sphingomyelin lub taub hau pab pawg los ntawm ib pawg ntawm sphingomyelinases (SMase). Cov enzymes no txawv raws li qhov zoo tshaj pH thiab/los yog subcellular qhov chaw. Sphingolipids yog cov sphingolipids ntau tshaj plaws hauv cov tsiaj. Nws yog ib qho tseem ceeb ntawm ceramides.

 

● Txoj Kev Rov Qab Los

Ceramide Powder Bulkkuj tuaj yeem tsim los ntawm kev tsis ncaj qha catabolism ntawm lwm cov sphingolipids complex. los ntawm ntau txoj hauv kev hu ua sphingolipid recycling lossis remediation pathways. Cov sphingolipids siab dua (sphingomyelins thiab glycosphingolipids) yog degraded los ntawm cov neeg nyob hauv enzymes (acidic SMase thiab acidic -glucosidase 1) nyob rau hauv lub lumen ntawm acidic hlwb los tsim ceramides. Ceramide degrades nws tus kheej mus rau sphingosine thiab dawb fatty acids uas muaj peev xwm nkag mus rau cytoplasm. Ib zaug nyob rau hauv cytoplasm, sphingosine hloov rov qab mus rau ceramide los ntawm ceramidase.

 

Muaj nuj nqi:
Ceramide 3 muaj nyob rau hauv tag nrho cov hlwb eukaryotic. Nws muaj lub luag haujlwm tseem ceeb hauv kev ua haujlwm hauv lub neej xws li kev sib txawv ntawm tes, kev loj hlob, apoptosis thiab kev laus. Ceramide yog siv raws li ib feem tseem ceeb ntawm intercellular lipids nyob rau hauv txheej corneum ntawm daim tawv nqaij. Nws tsis yog tsuas yog mus raws li qhov thib ob courier particle nyob rau hauv txoj kev sphingolipid, tab sis kuj tseem xav tias yog ib feem tseem ceeb thaum lub sij hawm siv epidermal txheej corneum txoj kev loj hlob. Nws muaj lub luag haujlwm hauv kev tswj cov tawv nqaij barrier thiab moisturizing ntawm daim tawv nqaij.

 

● Kev tuav cov tawv nqaij barrier
Ceramide yog ib feem tseem ceeb ntawm cov epidermis. Nws suav tias yog ib feem tseem ceeb hauv kev ua kom muaj homeostasis hauv lub cev. Lub peripheral txheej ntawm epidermis, txheej corneum, thav duab ib qho kev cuam tshuam ntawm sab nraud huab cua thiab lub cev sab hauv. Qhov kev muaj peev xwm cuam tshuam no ua rau muaj kev xav tau sib txawv, suav nrog kev tiv thaiv dej tsis zoo thiab tiv thaiv kev puas tsuaj sab nraud. Ceramides yog cov lipids loj uas tsim txog li 50% ntawm cov ntsiab lus lipid intercellular. Txheej corneum lipids yog qhov tseem ceeb rau kev ua raws li daim tawv nqaij ciam teb muaj peev xwm thiab tiv thaiv kev tsis zoo ntawm cov dej transepidermal.

Kev hloov pauv hauv qib ceramide los yog muaj pes tsawg leeg yog txuam nrog cov kab mob ntawm daim tawv nqaij. Piv txwv xws li atopic dermatitis thiab psoriasis. Cov tshuaj tu tawv nqaij tshiab tau pib siv cov ceramides. Exogenously muab tshuaj ceramides tuaj yeem pab kho cov tawv nqaij ceramide. Qhov no tuaj yeem pab txhim kho kev ua haujlwm ntawm daim tawv nqaij los ntawm kev ua kom cov tawv nqaij hydration thiab txo cov dej transepidermal.

● Cellular Function
Kev sau ntawmceramide hmoov ntaunyob rau hauv hlwb hloov countless flagging zaus. Ceramides actuate rot lossis apoptosis hauv ntau hom cell. Cov kev tshawb fawb tau pom tias ceramides thiab lawv cov metabolites cuam tshuam rau kev zom cov cell.

Lub hauv paus txheej txheem uas ceramide hloov pauv cellular metabolism yog nws qhov tseem ceeb inhibition ntawm Akt, serine / threonine kinase. Nws yog ib qho tshwj xeeb nruab nrab hauv kev taw qhia txoj hauv kev uas txuas cov insulin thiab lwm yam kev loj hlob mus rau qhov kev qhia, kev ua, thiab subcellular faib ntawm cov zaub mov thauj cov protein. Ntxiv nrog rau kev sib kho cov khoom noj khoom haus, Akt qhib txoj hauv kev anabolic (xws li, glycogen thiab protein synthesis) thaum inhibiting catabolism. Akt kuj tseem ua kom muaj sia nyob thiab inhibits autophagy enzymes thiab ua rau muaj kev nce hauv cell loj hlob thiab ruaj khov. Muaj cov pov thawj loj hlob uas Akt tseem ua lub luag haujlwm hauv kev mob qog noj ntshav, kab mob plawv, Alzheimer's disease thiab ntshav qab zib hom 2.

 

Ceramide tswj mitochondrial muaj nuj nqi ntxiv rau Akt. Vim muaj kev sib kis tsis tu ncua ntawm ER-txuas nrog subcompartments (subcompartments uas ceramide biosynthesis paub tias tshwm sim). Nws sim ua kom subcellularly cais thiab cais mitochondria los txiav txim seb muaj ceramide lossis ceramide synthase yuav tsum tau ua tib zoo soj ntsuam. Txawm li cas los xij, ntau pawg tshawb fawb tau tshaj tawm tias mitochondria muaj ntau hom sphingolipids. Xws li ceramide. Txawm hais tias ceramide synthesized nyob rau hauv endoplasmic reticulum tuaj yeem ncaj qha mus rau lwm cov organelles, mitochondria lawv tus kheej nqa cov tshuab enzymatic tsim nyog rau kev tsim cov ceramide. Ceramide paub tias cuam tshuam nrog mitochondria kom induce apoptotic pathways los ntawm kev nce membrane permeability.

 

Daim ntawv thov:

● Cov khoom siv tawv nqaij:
Ceramide bulk hmoov yog siv dav hauv kev lag luam tu tawv nqaij. Nws pab khaws cov dej noo hauv daim tawv nqaij thiab tiv thaiv dryness thiab txhim kho daim tawv nqaij hydration. Txhawm rau ntxiv dag zog rau daim tawv nqaij lub ntuj barrier, nws tiv thaiv cov aggressors sab nraud thiab pab tswj cov tawv nqaij noj qab haus huv, supple.

 

● Cov Khoom Siv Kho Plaub Hau:

Ceramide kuj pom daim ntawv thov hauv cov khoom tu plaub hau. Nws ua haujlwm ntawm kev noj qab haus huv ntawm cov plaub hau ncej los ntawm kev ntxiv dag zog rau cov ntiv tes ntawm daim tawv nqaij thiab tiv thaiv kev tsis zoo ntawm qhov tsis zoo.

● Kev Kho Mob Dermatological:

Ceramide hmoov ntauyog siv nyob rau hauv ntau yam kev kho dermatological. Nws zoo heev yuav ua tau zoo rau cov mob xws li dermatitis, psoriasis, thiab dermatitis, qhov twg ntawm daim tawv nqaij muaj peev xwm ciam teb raug cuam tshuam. Ceramide-based creams, balms, thiab moisturizers tuaj yeem pab txo qis thiab kho cov tawv nqaij, txo cov kev mob tshwm sim thiab ua kom rov zoo dua.

● Pharmaceutical Applications:
Ceramide Powder muaj peev xwm siv tau tshuaj vim nws cov peev xwm organic. Kev tshawb fawb pom zoo tias ceramides yuav xav tau ib ntu hauv ntau cov txheej txheem ntawm tes, suav nrog cell hailing, apoptosis, thiab cuam tshuam. Cov kws tshuaj ntsuam xyuas kev siv cov ceramides hauv cov qauv thauj tshuaj, kho qhov txhab, thiab kev kho mob ntawm ntau yam teeb meem.

 

● Nutraceuticals thiab Supplements:
Ceramide kuj tau muab tso rau hauv nutraceuticals thiab kev noj haus ntxiv. Kev siv lub qhov ncauj ntawm ceramides tuaj yeem pab nrog kev txhim kho ntawm daim tawv nqaij ciam teb muaj peev xwm, hydration, thiab los ntawm thiab loj ntawm daim tawv nqaij noj qab haus huv los ntawm sab hauv. Nws raug lees paub los pab ua kom zoo ntawm daim tawv nqaij thiab tej zaum yuav muaj txiaj ntsig zoo rau cov neeg uas muaj tawv nqaij qhuav lossis tawv nqaij.

 

Factory & Pab Pawg:

 

Daim ntawv pov thawj

 

Ntim & Xa khoom

Cim npe nrov: Tuam Tshoj ceramide hmoov bulk manufacturers, lwm tus neeg, Hoobkas