Chic acid hmoov

Kua txiv tshabAkab cid SUpplier:

Guanjie Biotech tshwj xeeb hauv chic acid hmoov kev tshawb fawb, ua thiab xa tawm ntau tshaj 20 xyoo. Chic acid yog lub ntsiab tivthaiv ntawm cov kua qaub. Nws yog insoluble hauv dej, soluble hauv ethanol thiab acetic acid, khoom yog muaju dawb. Peb muaj peb tus kheej cov ntaub ntawv ua haujlwm thiab ob txoj kab ntau lawm, yog li qhov ua tau zoo tuaj yeem lav. Txais tos rau nug nrog peb yog tias koj txaus siab.

 

Khoom Taw Qhia:

Chicic acid co hmoov yog ib qho khoom noj kua txiv uas tau muab los ntawm cov khoom tsiaj, xws li nyuj lossis yaj. Chic acid hmoov muaj cov cim iab iab saj. Nws yog dav siv hauv kev lag luam kws tshuaj. Nws kuj tseem siv nyob rau hauv kev tshawb fawb biochemical thiab raws li kev txhawb nqa hauv cell kev cai xov xwm. Ib qho ntxiv, chic acr acid muaj cov kev siv yuav muaj nyob rau hauv kev tsim cov tshuaj pleev ib ce thiab ua khoom noj ntxiv.

 

COA:

Cov khoom	Kev qhia tshwj xeeb	Qho kawg
Kev tshwm sim	Ib qho hmoov dawb	Cov hmoov dawb
Kev txheeb xyuas (los ntawm HPLC)	Lub sijhawm khaws cia lub hauv paus ntsiab lus ntawm kev ntsuas HPLC Chromatogram tau txais nyob rau hauv cov xwm txheej tau piav qhia hauv seem 'Cov tshuaj ntsig ntsig txog kev tuav lub sijhawm ntawm lub Thawj xib fwb tseem ceeb tshaj plaws hauv kev daws teeb meem.	Daim pib
Melting taw tes	Xyoo 197 Degree -202 Qib	Xyoo 197.7 Degree -198.8 Degree
Poob rau ziab	Tsawg dua los yog sib npaug rau 1.0%	0.35%
Sulphated tshauv	Tsawg dua los yog sib npaug rau 0.20%	0.03%
Yam Khoom Uas Muaj Feem (Hplc)	Ntau dua los yog sib npaug rau 95% (purity)	97.41%
	Tsawg dua los yog sib npaug rau 2.0% (ib leeg siab dua)	0.98%
	Tsawg dua los yog sib npaug rau 5.0% (tag nrho cov)	2.59%
Assay (los ntawm lub kaum)	98.0%~101.0%	98.7%
Tag	Pom zoo

 

Kev tshuaj xyuas kev huv (cov tshuaj uas muaj feem xyuam) - TLC sim

1. Tus Qauv: Lithochholic Acid - nmt 0.1%

2. Kev sim qauv:

• Kis Tus Neeg Sawv Cev: Chloroform: Pob txha ua acetic acid: ntshiab dej=8}}}}}}}}}}}}}: 15: 0.5 sib xyaw.

• Kev Npaj Qauv Qauv:

①TET kev daws 1: Qhov hnyav hnyav tus qauv 0.40g chic acid hmoov, siv daws a<1>Cov kuab tshuaj thiab kho lub ntim rau 10ml. (40mg / ml)

②TET Cov Haum 2: Siv 1ML ntawm kev ntsuas daws 1 thiab dilute rau 10ml. (4mg / ml)

 

• Npaj cov kev daws teeb meem

① NotOtard daws 1 (Ntsuas CDCA): hnyav 40Mg (MG) ntawm CDCA qauv, yaj nrog kev daws teeb meem rau 10ml. (4mg / ml)

② NotOressard daws 2 (Weigh aba): Weigh 20Mg (mg) ntawm Lithophanic acid qauv, yaj nrog daws a, thiab kho lub ntim rau 10ml. Nqa 2ml ntawm cov tshuaj no hauv 100ml volumetric flask, thiab kho qhov ntim nrog daws a rau tus cim kab. (40ug / ml)

 

• Kev sim mob

①thin txheej phaj: Silica gel g

②COLOR tus tsim tawm: phosphomolybdic acid: ethanol=1: 5

③SPOT DESKLE QHOV TSEEB: 5THOM

④expansion: 16 ~ 18cm

 

• Txoj kev sim

① Muab cov txheej txheem daws teeb meem kom raug kuaj kom pom nyob rau hauv kev txiav txim rau TLC phaj, siv 5ul spotting raj kom pom lub phaj.

Mus rau hauv lub tog raj kheej chromatogy lub tog raj kheej nrog cov vapor uas tsis meej txog cov neeg sawv cev tsis meej. (li 1.5h).

③dry hauv qhov cub (txog li 120 degree) tom qab nthuav tawm txog 30 feeb

④④ter txau cov xim tsim tawm cov ntawv tshaj tawm rau hauv TLC phaj, kom qhuav nws hauv qhov cub (li 120℃thiab txheeb xyuas cov txiaj ntsig.

Daws ib<1>: acetone: dej ntshiab=9: 1

 

3. Kev sim ua tau

Lithophanic Acid: Lub ntsiab lus ntawm kev ntsuas daws tau siab dua li qhov taw tes ntawm tus qauv (tsaus, lub teeb)

 

Kev soj ntsuam kev tshuaj xyuas (cov tshuaj uas muaj feem xyuam ⅱ) {-} kua theem

1. Txuj Ci

● Cov neeg muaj feem ntsig: nmt1.5% (thaj tsam%)

Lwm yam tshuaj tag nrho: NMT5.0% (thaj tsam%)

 

2. Kev sim txuj ci

● Txawb theem: Acetoniturile: Kev daws teeb meem tsis zoo: Methanol {}}}}: 37:40

● Kev Npaj Kev Ntsuas: hnyav 120mg ntawm chic acid hmoov qauv, yaj nrog rau kev daws teeb meem, thiab ntim rau 20ml.

● SILUTION Solution: Methanol: Mobile theem=10: 90

● Cov kua twm: 0.78g ntawm sodium dihydrogen phosphate, yaj hauv 1l ntawm dej ntshiab, phosphoric acid tuaj yeem hloov kho PH txiaj ntsig ntawm 3.

● Cov ntsiab lus yuav tsum raug tswj xyuas thaum tus nqi ntawm mobile theem ua tau nce ntxiv

● Kev sim sim

⑤ CARCOLUM: 4.6mm × 250mm, 5μmC18

⑥temperature: 40 Degree ± 1 degree

⑦detector: Cov dav dav dav dav (RID) (35℃± 1 degree)

⑧ txaus: 0.8ml / min (CDCA khaws cia sijhawm txog 42min)

Ofection Ntim: 75ul

Elaanalysis Sij Hawm: 60min

 

Daim Ntawv Thov:

Chic acid hmoov, lub ntuj bile acid muab tau los ntawm cov khoom tsiaj, muaj ntau yam kev siv hla kev sib txawv. Nrog nws cov yam ntxwv tshwj xeeb thiab cov haujlwm, nws pom cov nqi hluav taws xob hauv cov tshuaj, kev tshawb fawb biochemical, kab lis kev cai ntawm tes, tshuaj pleev ib ce, thiab kev lag luam khoom noj.

Kws Kev Lag Luam:
Nyob rau hauv lub xeem kws tshuaj, chic acid lub luag haujlwm yog oblub yog oblub: raws li ib qho khoom siv tshuaj (api) thiab ua ib qho kev tsim qauv.

• Nquag ua kom muaj khoom xyaw:

Lim chic acid yog lub hauv paus kev kho mob rau kev kho mob hauv lub pob hluav taws xob tsis raug ntawm cov khoom siv kua dej acrTsebresis, xws li xanthomatosis (ctx). Hauv cov neeg mob uas muaj ctx, muaj qhov tsis xws caj ces tiv thaiv cov Endogenous ntau lawm ntawm txaus cholic acid, ua rau cov kev sib txuam ntawm cov tshuaj lom neeg hauv kev sib tw. Kev tswj cov kua txob chic hmoov li cov tshuaj noj (piv txwv li cov tshuaj ntsiav uas tsis zoo, thiab tiv thaiv kev cuam tshuam ntawm cov pa hluav taws xob tsis zoo thiab mob plawv. Qhov no sawv cev rau ib lub neej - hloov kev kho rau cov tib neeg.

• Tsim kom zam:

Tshaj dhau nws cov kev siv tshuaj kho, chic acid thiab nws cov ntsev (piv txwv li, sodium cholity) yog ua haujlwm raws li ntuj sawv daws cov neeg sawv cev. Lawv tau koom nrog cov qauv tshuaj txhawm rau txhim kho cov xyoob ua tsis zoo ntawm cov dej tsis zoo {}} Soluble cov kev ua haujlwm. Los ntawm kev tsim micelles, chic acid tuaj yeem encapsulate tshuaj, tso cai rau lawv yuav tsum nqus tau hauv tsev aqueous ntawm lub zom zaub ntsuab, yog li nce lawv cov txiaj ntsig.

Kev tshawb fawb thiab microbiological

Hauv cov kev tshawb nrhiav chaw tshawb xyuas, chicic acid hmoov yog qhov tsis tseem ceeb reagent.

• Cov protein ntau ntxiv:

Nws cov tshuaj ntxuav tau cov khoom siv tau ua tiav rau soluburilize membrane cov protein thiab lipids. Cov kws tshawb fawb siv nws kom tawg cov xovtooj ntawm tes thiab cais tawm hauv cov membrant thiab kev kawm yam tsis muaj qhov tseem ceeb rau kev nkag siab lawv cov qauv.

• Cov Kev Kawm Txog Kev Kawm:

Raws li cov kev tshawb fawb txog cov kua dej classic, nws yog siv ntau yam hauv Biophysical kev kawm kom nkag siab cov ntsiab cai ntawm Fichle tsim, tseem ceeb rau kev tshawb fawb hauv Lipidomics thiab Nanotechnology.

• Microbiological Media ntxiv:

Hauv bacteriology, tshwj xeeb cov ntsev, suav nrog cholic acid doltivatives, yog ntxiv rau kab lis kev cai xov xwm ua cov neeg sawv cev xaiv. Lawv inhibit txoj kev loj hlob ntawm gram - Cov kab mob zoo (zoo li cov kab mob enterobacteriaae thaum tso cai rau cov pathogens li salmonella thiab E. coli.

Kev coj noj coj ua mov ntawm tes

Hauv kev ua haujlwm cell advanced cell tshwj xeeb, tshwj xeeb hauv qia cell kev tshawb fawb thiab kev tswj hwm cov xov tooj ntawm tes tshwj xeeb, chic acid yog siv los ua kev txhawb nqa hauv cov kab lis kev cai xov xwm. Nws pab nyob rau hauv kev nqus ntawm lipids thiab rog-} Soluble vitamins los ntawm lub hlwb, mimicking lub ntuj ntawm lub cev ib puag ncig ntau dua. Qhov no yog qhov tshwj xeeb tshaj yog rau Hepatocyte (hepatocyte (hepalocyte (hiver cell) kev coj noj coj ua, qhov twg yog Lipid Metabolism yog qhov tseem ceeb rau kev tswj hwm kev noj qab haus huv ntawm tes, kev ua haujlwm, thiab kev sim raug.

Kev Ua Kom Zoo Nkauj thiab Kev Lag Luam Saib Xyuas Kev Lag Luam

Lub zog surfactant ntawm chicic acid hmoov yog siv hauv cov tshuaj pleev ib ce thiab tawv nqaij tawv.

• Emulsification:

Nws pab tsim cov emulsions ruaj khov, kom ntseeg tau tias roj thiab dej {- raws cov khoom xyaw hauv cov tshuaj pleev, cream, thiab serums tsis cais.

• Kev Nkag Siab Ua Si:

Zoo ib yam li daim ntawv thov tshuaj, nws tuaj yeem txhim kho cov tawv nqaij nqus ntawm lwm cov tshuaj xyaw ua haujlwm hauv cov qauv, xws li cov vitamins lossis cov tshuaj tua kab mob antioxidants, muaj peev xwm nce ntxiv cov khoom lag luam zoo.

• Keeb kwm yog keeb kwm:

Raws li ib qho chaw sib txuas los ntawm qhov xwm, nws yog feem ntau ua lag luam ua biocompibrative thiab ntuj xaiv rau hluavtaws surfactants.

Kev Lag Luam Khoom Noj

Thaum nws siv tau ntau dua niche, chic acid hmoov ua haujlwm ua kev pabcuam ua haujlwm hauv kev lag luam khoom noj.

• Emulsifier:

Nws tuaj yeem siv tau hauv feeb kom muaj emulsify cov rog thaum kev tsim khoom ntawm qee yam zaub mov, tsim kom muaj kev sib cais thiab tiv thaiv kev sib cais.

• prefursor rau synthetic sweeteners:

Feem ntau, nws tuaj yeem ua cov khoom pib rau cov khoom siv ntawm cov khoom nruab nrab ntawm {{}} siv cov tshuaj sweethers.

 

 

Hoobkas & team team:

 

Daim ntawv muaj cai

 

Pob & Xa Khoom

Cim npe nrov: Chic acid hmoov, Suav teb Cholic acid hmoov tuam ntxhab, cov chaw muag khoom, Hoobkas