L-theanine hmoov

Lus Taw Qhia

Pure L-theanine hmoov, tshuaj lub npe yog N-ethyl- -L-glutamine, uas yog ib tug yam ntxwv uas tsis yog-protein amino acid ntawm tshuaj yej tsob ntoo. Tam sim no, nws tsuas yog qhia hauv Xerocomus badius thiab qee cov nroj tsuag camellia (Camellia japonica thiab Camellia sasanqua). Theanine yog qhov tseem ceeb ntawm cov amino acids dawb hauv tshuaj yej. Cov kev tshawb fawb tau pom tias theanine suav txog li 70% ntawm tag nrho cov amino acids dawb hauv cov nplooj tshiab tua, thiab cov ntsiab lus theanine hauv nplooj tshiab suav txog li 1 ~ 2% ntawm qhov hnyav qhuav ntawm nplooj nplooj.

Before the tea tree shoots germinate, the ammonia nitrogen supplied to the tea tree is mainly stored in the roots and leaves as theanine, glutamine and arginine. These compounds are transferred to the growth point (new shoot) when the tea tree germinates. Especially Theanine has the highest concentration. From the perspective of tea plant parts, theanine exists in various organs of tea plants except fruit, and the concentration is: young leaves> root bark, absorbing roots> absorbing roots> old leaves>stem bark thiab paus thiab qia xylem. Nyob rau hauv cov nqe lus ntawm lub caij, nws yog qhov siab tshaj plaws nyob rau hauv caij nplooj ntoos hlav, ces maj mam poob, thiab ces nce me ntsis nyob rau hauv lub caij nplooj zeeg; Nyob rau hauv lub caij ntuj no, theanine feem ntau accumulates nyob rau hauv cov hauv paus hniav ntawm tshuaj yej tsob ntoo, thiab thaum lub sij hawm germination ntawm tshuaj yej tsob ntoo nyob rau hauv caij nplooj ntoos hlav, cov ntsiab lus ntawm theanine nyob rau hauv cov hauv paus hniav ntawm tshuaj yej tsob ntoo txo, qhia hais tias nws yog pauv mus rau tshiab tua.

 

Vim li cas thiaj xaiv peb?

Lub zog ntawm kev lag luam, lub hauv paus chaw tsim khoom, thiab kev tswj kom zoo, tuaj yeem hloov kho rau ntau yam kev qhia tshwj xeeb raw cov hmoov, ntshiab hmoov, proportional extract, thiab txheem extract, SC cov ntaub ntawv pov thawj Hoobkas khoom xyaw manufacturers. Peb tuaj yeem muab cov txheej txheem xeem thiab cov ntaub ntawv pov thawj ntawm lub Hoobkas. Peb muaj lub chaw soj nstuam ywj pheej, txhawb kev ua cov khoom tuaj, thiab tuaj yeem hloov kho cov qauv ntawm kev thov txhua lub sijhawm. Koj tuaj yeem tuaj xyuas peb lub Hoobkas txhua lub sijhawm. Peb tuaj yeem muab cov khoom zoo rau koj ntawm tus nqi zoo tshaj. Yog tias koj txaus siab rau pebL-theanine hmoovcov khoom, thov koj xav tiv tauj peb:info@gybiotech.com

 

COA

Yam khoom	Specification	Kev tshwm sim	Txoj kev
Cov ntaub ntawv tseem ceeb ntawm cov khoom
Genus thiab Hom	Camellia sinensis	Ua raws	/
Ib feem ntawm tsob nroj	Nplooj	Ua raws	/
Lub Tebchaws Keeb Kwm	Tuam Tshoj	Ua raws	/
Marker Compounds
L-theanine	>98.0%	98.76%	HPLC
Cov ntaub ntawv Organoleptic
Qhov tshwm sim	Hmoov	Ua raws	NLS-QCS-1008
Xim	Dawb mus rau dawb	Ua raws	GB/T 5492-2008
tsw	Yam ntxwv	Ua raws	GB/T 5492-2008
Saj	Yam ntxwv	Ua raws	GB/T 5492-2008
Cov ntaub ntawv txheej txheem
Txoj kev ua	Kev rho tawm	Ua raws	/
Solvent(s) siv	Ethanol & Dej	Ua raws	/
Txoj Kev Qhuav	Nqus kom qhuav	Ua raws	/
Excipient	Tsis muaj	Ua raws	/
Ratio ntawm Extraction	80:1	Ua raws	/
Cov yam ntxwv ntawm lub cev
Melting point	214-215 degree	2 14.5 degree	GB21781-2008T
Solubility	Soluble hauv dej	Ua raws	Pom kev
Particle Loj (80 mesh)	98.0% dhau 80 mesh	Ua raws	GB/T 5507-2008
Moisture	<2.0%	1.2%	GB/T 14769-1993
Tshauv Ntsiab Lus	<1.0%	0.4%	AOAC 942.05, 18
Solvent Residue	Tsis muaj	Ua raws	NLS-QCS-1007
Hnyav Hlau
Total Heavy Metals	<10 ppm	Ua raws	USP<231>, method II
Arsenic	<1.0 ppm	Ua raws	AOAC 986.15, 18
Coj	<1.0 ppm	Ua raws	AOAC 986.15, 18
Mercury	<0.5 ppm	Ua raws	AOAC 971.21, 18
Tshuaj tua kab
666	<0.2ppm	Ua raws	GB/T5009 19-1996
DDT	<0.2ppm	Ua raws	GB/T5009 19-1996
Microbiology
Tag nrho cov phaj suav	<1,000cfu/g	72 cfu/g ib	AOAC 990.12, 18
Total Poov & Pwm	<100cfu/g	10 cfu/g	FDA (BAM) Tshooj 18, 8th Ed.
E. Coli	Tsis zoo	Tsis zoo	AOAC 997.11, 18
Salmonella	Tsis zoo	Tsis zoo	FDA (BAM) Tshooj 5, 8th Ed.

 

 

Cov qauv tshuaj ntawm theanine:

Raws li tuaj yeem pom los ntawm daim duab, ib qho molecule ntawm L-theanine Powder yog muab los ntawm ib lub molecule ntawm glutamic acid thiab ib lub molecule ntawm ethylamine, uas yog synthesized los ntawm generating peptide bonds los ntawm shrinkage. Ntuj theanine feem ntau yog L-theanine, yog li nws feem ntau tso tawm ua lus Askiv li: L-Theanine.

 

Metabolic txoj kev ntawm theanine hauv tshuaj yej tsob ntoo

1 Lub synthesis thiab metabolism ntawm theanine

Raws li perennial ammonium-hloov kev lag luam qoob loo, tshuaj yej tsob ntoo muaj ib txoj hauv kev sib txawv nitrogen metabolism los ntawm lwm cov nroj tsuag, uas yog, tshuaj yej tsob ntoo nitrogen metabolism thiab theanine metabolism yog sib txuas. Txhawm rau kom paub meej txog qhov tseem ceeb ntawm lub cev ntawm cov tshuaj yej tsob ntoo nitrogen metabolism txoj hauv kev nrog theanine ua lub hauv paus, cov kws tshawb fawb Nyij Pooj tau tshawb nrhiav txoj hauv kev theanine metabolic hauv cov tshuaj yej tsob ntoo los ntawm xyoo 1960 txog rau xyoo 1980, thiab cov txiaj ntsig kev tshawb fawb tau sau tseg raws li hauv qab no. :

 

Raws li tuaj yeem pom los ntawm daim duab saum toj no, txoj kev metabolic ntawm theanine hauv tshuaj yej tsob ntoo tuaj yeem piav qhia ua ob ntu: hauv paus synthesis thiab nplooj decomposition, uas yog:

Ⅰ.Alanine nyob rau hauv lub hauv paus ntawm tshuaj yej tsob ntoo yog decarboxylated nyob rau hauv qhov kev txiav txim ntawm alanine decarboxylase los tsim ethylamine;

Ⅱ.Tom qab ntawd L-glutamic acid thiab ethylamine yog catalyzed los ntawm theanine synthase los tsim theanine;

Ⅲ.Theanine yog thauj mus rau nplooj los ntawm qia, thiab generates L-glutamic acid thiab ethylamine nyob rau hauv qhov kev txiav txim ntawm theanine hydrolase;

Ⅳ.Ethylamine yog oxidized rau acetaldehyde nyob rau hauv qhov kev txiav txim ntawm amine oxidase, thiab koom nyob rau hauv lub metabolism ntawm nplooj catechins. (acetaldehyde tuaj yeem koom nrog hauv catechin metabolism)

 

2 Qhov chaw ntawm precursors rau theanine synthesis

Ntshiab l-theanine hmoov yog synthesized los ntawm glutamic acid thiab ethylamine, yog li nws cov hluavtaws precursors yog glutamic acid thiab ethylamine, li cas los lawv tuaj?

Ⅰ.Ethylamine yog muab los ntawm alanine los ntawm alanine decarboxylase, thiab pawg carboxyl (carbon dioxide) raug tshem tawm los tsim ethylamine. Txoj kev tshawb nrhiav pom tias theanine feem ntau yog tsim los ntawm cov hauv paus hniav, tab sis tsis nyob hauv nplooj. Alanine tuaj yeem tsim los ntawm cov metabolism (deamination lossis deacidification) ntawm lwm cov amino acids.

 

II Qhov chaw ntawm glutamic acid:

Txoj hauv kev rau glutamate synthesis los ntawm glutamine synthase/glutamine- -ketoglutarate aminotransferase (EC 1.4.1.14, glutamate synthase) hauv cov nroj tsuag siab dua yog txoj hauv kev tseem ceeb rau ammonia assimilation (hu ua GS/GOGAT txoj kev). Lub enzyme deaminates glutamine thiab reacts nrog alpha-ketoglutarate los tsim ob molecules ntawm glutamate.

 

Ntxiv nrog rau txoj hauv kev tseem ceeb, muaj lwm txoj hauv kev pabcuam:

Hauv cov nroj tsuag, glutamate dehydrogenase (EC 1.4.1.2) catalyzes lub reductive amination ntawm -ketoglutarate los tsim glutamate.

 

Kuj tseem muaj kev siv alanine aminotransferase (EC 2.6.1.2) hauv tshuaj yej los ua cov tshuaj alanine thiab -ketoglutarate los tsim pyruvate thiab glutamate.

Pharmacological teebmeem ntawm theanine (piv txwv li)

Raws li kev tshawb fawb tam sim no, Pure L-theanine hmoov muaj cov tshuaj pharmacological xws li tiv thaiv kab mob plawv, cuam tshuam rau lub paj hlwb, tswj cov ntshav qab zib, kev kho mob ntxiv lossis kho cov qog nqaij hlav, antioxidant thiab kev tiv thaiv ntawm tes. Ntawm lawv, daim ntawv thov ntawm theanine los kho kev nyuaj siab thiab txhim kho kev pw tsaug zog tau dhau los ua lub ntsiab lus kub ntawm kev tshawb fawb nyob rau hauv xyoo tas los no, thiab daim ntawv thov ntawm theanine thiab nws cov derivatives rau adjuvant doxorubicin hauv kev kho cov qog kuj muaj peev xwm tshawb fawb tus nqi. Tsis tas li ntawd, cov kws tshawb fawb kuj pom tias theanine tuaj yeem pab cov neeg haus luam yeeb ntev ntev txiav luam yeeb rau qee yam.

Tam sim no, cov txheej txheem ntawm kev txiav txim ntawm theanine tau pom meej meej:

● Tswj cov piam thaj thiab lipid metabolism los ntawm insulin thiab AMPK (AMP-active protein kinase) thiab lawv cov kev taw qhia nqes dej;

● Los ntawm kev sib tw nrog glutamate rau receptors, nws inhibits neurotoxicity thiab neuroprotection tshwm sim los ntawm qhov nce ntawm glutamate concentration;

● L-theanine Powder txhim kho kev pw tsaug zog thiab tswj lub siab los ntawm kev ua kom lub hlwb tsis muaj zog thiab txo qis -b hlwb tsis muaj zog;

● inhibit kev loj hlob thiab metastasis ntawm cov qog hlwb los ntawm down-regulating qhov piv ntawm Bcl-2/Bax protein (apoptosis inhibitory gene / apoptosis txhawb cov noob) hauv qog hlwb;

● Kev tiv thaiv cov hlwb ib txwm los ntawm kev tiv thaiv oxidation thiab inhibition ntawm apoptosis caspase-3 protein.

 

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Cim npe nrov: L-theanine hmoov, Tuam Tshoj l-theanine hmoov manufacturers, lwm tus neeg, Hoobkas