Citrus Aurantium extract hmoov

Citrus aurantium extract hmoov khoom

Guanjie Biotech tau yog ib qho Citrus aurantium extract hmoov khoom rau 20 xyoo. Peb cov citrus citrus aurantium extract yog los ntawm Rutaceae Citrus nroj tsuag qab txiv kab ntxwv, thiab txiv qaub. Nov yog ib daim ntawv ntawm lub teeb daj zoo hmoov. Peb muaj cov kev sib txawv. Peb pawg neeg paub dhau los siv HPLC kuaj kom lav cov khoom ruaj khov thiab ua tau zoo, nrog cov ntawv ceeb toom muaj thaum thov txog. Thov nco tseg: Cov khoom siv no sib txuam nrog cov neeg sawv cev oxidizing muaj zog. Yog tias koj txaus siab rau peb cov khoom, thov koj xav tiv tauj peb:info@gybiotech.com.

Vim li cas thiaj xaiv Guanjie Biotech?

● Peb yog ib qho ntawm cov ua nroj tsuag extract citrus aurantium extract hmoov chaw muag khoom, kev koom ua ke R & D, ntau lawm, thiab kev muag khoom.

● Peb ua raws li txoj kev pab rau kev ua lag luam "Zoo ua ntej, cov neeg siv khoom ua ntej", thiab ua kev koom tes nrog koj.

● Peb lub Hoobkas tuaj yeem ntim cov khoom tseem ceeb thawm xyoo los tiv thaiv kev ncua qeeb.

Proport kev ua haujlwm shipping kom ntseeg tau tias cov khoom tuaj yeem raug xa tawm kom nyab xeeb thiab nrawm.

 

Coa

● Hesperidine 95%

Yam ntsuas xyuas	Kev qhia tshwj xeeb	Qho kawg
Assisy (hesperidine, UV)	Ntau dua los yog sib npaug rau 95.0%	95.00%
Kev Siv Lub Cev & Tshuaj Tswj
Botanical Npe	Citrus Sinenis Osbeck	Ua raws
Siv Hauv	Txiv	Ua raws
Daim qhia npe	Yam zoo	Ua raws
Kev tshwm sim	Daj - xim av zoo hmoov	Ua raws
Saj	Tus yam ntxwv	Ua raws
Poob rau ziab	Tsawg dua los yog sib npaug rau 5.0%	3.00%
Txhos	Tsawg dua los yog sib npaug rau 1.5%	0.26%
Hnyav Hlau	<10ppm	Ua raws
Xws li	<2ppm	Ua raws
Residual cov kuab tshuaj	EUR.Pharm.	Ua raws
Tshuaj tua kab mob	Tsis zoo	Tsis zoo
Me lug
Tag Nrho Cov Phaj Suav	<1000/g	60/g
Poov koob & pwm	<100/g	<10/g
E.coli	Tsis zoo	Ua raws
Tus ntses siav	Tsis zoo	Ua raws

 

Molecular Source:

Citrus aurantium extract hmoov hesperidin yog synthesized los ntawm hesperidin thiab sawv los ntawm kev tshem tawm cov dej ntawm cov dej los ntawm kev ua haujlwm biological nyuaj

C16H14O6+C12H22O10→C28H34O15+H2O

 

Flow chart:

Kev txiav txim siab ntawm Hesperidin

A.1.1 Reegents

Methanol: ntshiab ntshiab; Acetoniturile: ntshiab kom dawb huv si; Phosphoric acid: Super dawb; Cov dej huv siab.

A.1.2 Ntsuas cov kua txwv li kua taub hau me ntsis, ultrasonic nqus tsev ntxhua khaub ncaws

A.1.3 Chromatographic mob

Chromatographic kem: 250 * 4.6mm ODS-3

Txawb theem: Acetoniturile: Dej: Methanol: Phosphoric Acid {{}}: 79.6: 0.01

Flow tus nqi: 1.5ml / min

Wavelength: 28Lhe concentrationNtawm Citrus Aurantium extract hmoov hesperidin qauv ua haujlwm daws: 0.1mg / ml (methanol daws)

 

A.1.4 Cov kauj ruam xeem

Nqa 10 tsiav tshuaj thiab sib tov lawv nyob rau hauv lub cug

A.1.5 Kwv Tawm

                      C_{lub hom phiaj}                V_{lub hom phiaj}              V

X (mg / 100g)= ------ × h_{khoom sim} ×  -------  × --- ×100

H qhov qauv                 V_{khoom sim}              W

 

X: Cov ntsiab lus ntawm hesperidin hauv cov hnoos qeev (mg / 100g)

C _{Lub hom phiaj}: Txuj Ci Tshuaj Convüration Mg / ML

H _{lub hom phiaj}: Peak Qhov Siab ntawm Cov Qauv Qauv

H _{Khoom sim}: piv txwv li qhov siab dua

V_{lub hom phiaj}: Cov Qauv Ua Kua Hluav Taws Xob Ntim UL

V _{khoom sim}: Qauv Tawm Xov Tooj UL

V: Qauv tsis tu ncua ntim ML

W: Qauv hnyav g

 

Txuj Ci Ntau LawmRau hesperidin thiab hesperetin los ntawm txiv kab ntxwv tev

Cov ntaub ntawv no qhia ob txoj hauv kev rau kev rho tawm cov tebchaw ntawm cov txiv kab ntxwv qhuav. Lub tebchaw tseem ceeb yog citantium aquantium extract hmoov hesperidin, ib glycoside, thiab hesperetin, nws aglycone counterpart.

Txoj Kev 1: Ntau Lawm Hesperidin Hmoov

Citrus aurantium extract hmoov yog ib txwm pom nyob rau hauv cov peels ntawm cov txiv ntoo uas zoo li txiv kab ntxwv zoo li txiv kab ntxwv thiab txiv qaub. Cov qauv no piav qhia txog nws cov kev rho tawm los ntawm ziab, siav cov txiv kab ntxwv pels.

● Npaj:

Ua ntej, cov txiv kab ntxwv qhuav tev yog coarsely tws. Nws yog ces soft nyob rau hauv 3 mus rau 6 zaug nws qhov hnyav hauv dej li 30 feeb los ua muag.

● Alkaline Extraction:

Mus rau cov taum muag muag, 4-10% txiv qaub (calcium hydroxide) thiab 7-12 npaug cov dej ntxiv. Qhov sib tov yog starred, thiab cov pH yog soj ntsuam thiab kho rau ib qho alkaline ntau ntawm 11.5 txog 12.0 siv txiv qaub lossis sodium hydroxide. Nws soaks rau 1.5 txog 2 teev.

Ringration thiab ntxuav:

Cov sib tov yog centrifugally lim. Cov lim lim dej nplua yog ntxuav dua nrog 5-7 zaug nws qhov hnyav hauv dej, thiab lub p yog rov qab nyeem rau 11.5-12 rau kev soaking thib ob thiab pom. Qhov rov ua kom txog thaum cov kev ua kom pom tseeb.

● Nag ntuj nag: Cov kev sib xyaw ua ke filtrate yog acidified rau pH 5 siv dilute hydrochloric acid. Tom qab sawv rau ob hnub, ib cov ntaub ntawv los daus.

● Kev ua kom huv thiab ziab:

Cov nag lossis daus tau sau thiab ntxuav nrog dej kom txog thaum kev daws teeb meem yog ze li ntawm nruab nrab. Qhov no yog cov neeg sib cav sib ceg. Txhawm rau huv nws, cov khoom uas cov crudolved nyob rau hauv kev daws ntawm 1% sodium hydroxide hauv 50% ethanol thiab lim. Qhov freattrate yog re-}} acidified rau pH 5 nrog hydrochloric acid los nag dawb. Cov nag kawg yog ntxuav, qhuav ntawm 70 degree, crushed, thiab sieved rau hauv ib qho hmoov. Tag nrho cov txiaj ntsig yog 0.6% rau 1.8% ntawm thawj cov txiv kab ntxwv tev tev hnyav.

 

Txoj Kev 2: Ntau Lawm Hesperetin

Hesperetin yog muab tau los ntawm Citrus aurantium extract hmoov hesperidin los ntawm cov txheej txheem uas tawg cia nws cov qauv.

 

● Alkaline hydrolysis:

Ntxhuav cov txiv kab ntxwv tev hmoov yog tov nrog dej thiab txiv qaub. Lub PC yog hloov kho rau ib qho kev sib tw ntau heev ntawm 12 txog 13 siv 25% sodium hydium ydrroxide tov. Qhov no sib tov soaks rau 10 txog 12 teev.

Kev lim dej: cov kua yog nias thiab sau, thaum cov khoom seem tsis muaj pov tseg.

● Cov cua sov:

Cov PH ntawm cov kua filtrate yog txo qis rau 3-4 uas siv concotrated hydrochloric acid. Qhov kev daws acidic no yog tom qab ntawd ua kom sov thiab khaws cia ntawm 70℃rau 30 feeb.

● Nag los nag dej thiab ziab:

Txoj kev daws tau txias thiab tso cai rau sawv ntsug kom txog thaum muaj kev kub ceev ua tiav. Cov khoom siv nag lossis nag los tau sau rau ntawm kev nqus cov dej, ntxuav nrog dej kom txog thaum nruab nrab, thiab qhuav ntawm 80 degree. Qhov no ua rau muaj kev sib cav sib ceg.

● Purification:

Citrus aurantium extract hmoov zoo nkauj huv siab Hesperetin yog tau los ntawm recrystallizing cov khoom crude uas siv methanol raws li cov kuab tshuaj.

 

Pharmacological effect:

Txo cov dej ntshiab thiab papyability ntawm capillaries, thiab nws yog siv rau kev kho cov citrus Nws tuaj yeem txhim kho kev txo qis ntawm capillary tiv taus (txhim kho cov nyhuv ntawm vitamin C). Nws muaj anti {- mob thiab cov tshuaj tiv thaiv, nrog rau cov roj aldehyde uas tuaj yeem tiv thaiv Frostbite thiab inhibit ras lens. Nws muaj cov haujlwm ntawm kev ntxiv dag zog rau lub plab, tshem tawm phlegm, tshem tawm hnoos, thiab diuresis thiab mob plab thiab mob plab.

 

Rooj mov:

● Citrus aurantium extract hmoov muaj antioxidant, anti {{{{

● Nws tuaj yeem tsim cov enzymes tom qab: phospholipase A2, Lipoxygenase, hmg-}} oxygenase.

● Nws txhim kho kev noj qab haus huv ntawm cov hlab ntsha los ntawm kev txo cov kab mob hauv cov pa hluav taws xob.

● Citrus aurantium extract cov hmoov cov khoom siv tau siv los txo cov quav hniav kub thiab lwm yam kev ua xua los ntawm kev tawm ntawm cov tshuaj antamine los ntawm mast hlwb. Qhov ua tau los tiv thaiv {{- Cancer kev ua haujlwm ntawm Hesperidins tuaj yeem piav qhia los ntawm kev txwv ntawm polyamine synthesis.

● Txiv kab ntxwv Flavone cov khoom xws li cov duab uas muaj ntxhiab, dej zoo, thiab pom tseeb pharmacological nkaus

● Citrus aurantium extract hmoov tuaj yeem ua kom muaj lub siab ntsws ua kom muaj lub siab ntsws, thiab tom qab ntawd ua rau ntshav siab.

 

Daim Ntawv Thov:

Citrus aurantium extract hmoov muaj cov haujlwm tiv thaiv thiab cov kab mob hlwb, cov tshuaj tua kab mob ntawm lub cev, tshuaj tiv thaiv kab mob ntawm lub cev, anti {in inflammatory cuam tshuam, thiab cov tshuaj tiv thaiv kab mob

 

Peb Lub Hoobkas:

Muaj ob lub chaw ua haujlwm, ob leeg hauv nroog Baoji thiab Shanguo City. Guanjie cov tuam txhab npog thaj tsam ntawm 7000㎡, suav nrog GMP tus qauv kev ua haujlwm ntawm 2000㎡. NMN NMN hmoov zoo yog tsim nyob rau hauv ib puag ncig ua hauj lwm huv, thiab txhua kauj ruam ntawm cov txheej txheem yog ua los ntawm cov kws tshaj lij muaj txuj ci siab. Ob qho tib si txheej txheem ntawm kev tsim khoom thiab cov khoom lag luam nws tus kheej tau raws txhua tus qauv thoob ntiaj teb.

 

Cov Khoom Tsim Kho

Hesperidin Tej yam hmoov yog tsim nyob rau hauv ib puag ncig ua hauj lwm huv thiab txhua kauj ruam ntawm cov citrus aurantium extract cov txheej txheem ua haujlwm los ntawm cov kws tshaj lij.

 

Kuaj Chaw:

Ob qho txheej txheem ntau lawm ntawm kev tsim khoom thiab cov khoom lag luam nws tus kheej tau raws li cov qauv hauv ntiaj teb thoob ntiaj teb. Thiab yog tias koj xav tau daim ntawv qhia txog peb, peb tuaj yeem muab koj.

 

Daim ntawv muaj cai

Peb tau txais qhov tsis - gmo los ntawm cov pab pawg thoob ntiaj teb. Peb muaj ntawv pov thawj txog Halaal, ISO 9001, ISO 22000, kosher, PAHS, SC, thiab lwm yam.

 

Pob & Cia

(1) pob:

● 5-10kg / hnab: Yog tias koj xav tau 5-10KG, peb muab tso rau hauv ib lub thawv.

● 1Kg / hnab: Yog tias koj xav tau 25kg lossis ntau dua, peb muab lub hnab ci txhuas hauv peb lub nruas.

(2) cia:

Khaws cia kom deb ntawm lub teeb muaj zog thiab kub.

 

 

Kev xa khoom

Qhov rooj mus rau qhov rooj qhov kev pab cuam yooj yim khaws cov khoom muag thiab los ntawm hiav txwv, huab cua.

 

 

 

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