Curcumin Extract hmoov

Lus Taw Qhia

Curcumin extract hmoov yog diketone compound muab rho tawm los ntawm rhizome ntawm qee cov nroj tsuag hauv Ginger tsev neeg thiab Tennantaceae. Turmeric muaj 0. Curcumin muab 95 feem pua ​​​​Curcuminoids. Curcumin yog txiv kab ntxwv-daj crystalline hmoov, me ntsis iab, insoluble nyob rau hauv dej thiab ether, soluble nyob rau hauv ethanol, propylene glycol, yooj yim soluble nyob rau hauv glacial acetic acid thiab alkaline tov, reddish-xim av nyob rau hauv alkaline, daj nyob rau hauv nruab nrab thiab acidic. Curcumin muaj zog ruaj khov los txo cov neeg ua haujlwm, cov xim muaj zog, ib zaug xim, nws tsis yooj yim rau ploj, tab sis rhiab rau lub teeb, cua sov, hlau ions, lub teeb tsis kam, kub tsis kam, hlau ion kuj tsis zoo.

Nrog lub suab lag luam kev ruaj ntseg zoo, Guan jie ua raws li cov qauv kev tswj hwm nruj. Nws yog kuaj los ntawm HPLC, peb lub ncov hauv ntiv tes print.pure natural extract, USP txuj Peb yog ib pab neeg tshaj lij los tsim, tshawb fawb thiab muag ntawm Curcumin extract bulk hmoov. Peb muaj ntau qhov sib txawv ntawm cov khoom. Feem ntau tag nrho curcumin 10 feem pua ​​-95 feem pua ​​(CP version, USP version), dej soluble tag nrho curcumin 10 feem pua ​​-30 feem pua, turmeric oleoresin, turmeric oil, thiab lwm yam. Nws muaj cov yam ntxwv tsw ntawm turmeric, thiab cov hmoov yog daj los yog reddish. Peb tuaj yeem muab cov khoom lag luam zoo rau koj ntawm tus nqi zoo tshaj, raws li cov kws tshaj lij tshuaj ntsuab cov khoom lag luam, Guan jie yog koj qhov kev xaiv zoo tshaj.

COA

MOA:

Curcumin ntsiab lus (HPLC) txoj kev txiav txim

Summary of methodology

Tom qab cov qauv tau yaj los ntawm ultrasound, nws tau txiav txim los ntawm HPLC thiab ntsuas los ntawm cov txheej txheem sab nraud.

II. Cov cuab yeej thiab cov cuab yeej

Kev Ntsuas Ntsuas, (Sensitivity 0.00001g).

Ultrasonic tu ntsuas: 250W, 20kHz.

Kev ua haujlwm siab ua kua chromatography (nrog ultraviolet detector)

III. Reagents thiab kev daws teeb meem

① Acetonitrile. Chromatographic purity;

② Methanol; chromatographic purity;

③ glacial acetic acid; chromatographic purity;

④ HPLC qib dej lossis MILIQ dej;

4. Cov khoom siv ntawm curcumin: purity ntawm HPLC ± 98 feem pua.

Tsib Chromatographic Conditions thiab System Applicability

5.1 CHROMATOGRAPHIC CONDITIONS

A) Chromatographic kem: octadecylsilane bonded silica gel kem, 4.6 mm X 250 mm.

B) theem mobile: acetonitrile{{0}} feem pua ​​glacial acetic acid tov (48:52), lim los ntawm cov organic system 0.45 um lim membrane, thiab npaj los ntawm ultrasonic.

C) Tus nqi ntws: 1.00 ml / min.

D) nrhiav wavelength: 430nm.

E) Kem kub: 30 degree

5.2 System serviceability

Tus lej theoretical phaj yuav tsum tsis pub tsawg dua 4000 raws li kev suav ntawm curcumin ncov.

VI. Cov txheej txheem ua haujlwm

6.1 Sampling

Cov qauv no tau raug coj mus kuaj raws li txoj hauv kev hauv Daim Ntawv Ntxiv II A ntawm xyoo 2010 tsab ntawm Pharmacopoeia ntawm Cov Neeg Sawv Cev ntawm Tuam Tshoj.

6.2 Kev Npaj Kev Tswj Xyuas Kev daws teeb meem

Cov tshuaj siv ntawm curcumin (kwv yees li 10 mg) raug ntsuas kom raug, muab tso rau hauv 100 mL xim av lub raj mis, ultrasonic yaj nrog methanol thiab diluted mus rau qhov ntsuas kom tau txais cov tshuaj siv tshuaj ntawm 0.10 mg / ml.

6.3 Kev npaj cov kev daws teeb meem rau cov khoom kuaj

Siv ib qho tsim nyog ntawm turmeric extract hmoov (raws li cov ntsiab lus), ntsuas kom raug, muab tso rau hauv 100mL xim av lub raj mis, ntxiv txog 80mL methanol, extract rau 15 feeb los ntawm ultrasonic, tshem tawm, muab tso rau hauv chav tsev kub. , dilute nrog methanol mus rau lub teev, co zoo.Qhov kev ntsuam xyuas cov tshuaj yog tau los ntawm kev lim cov filtrate nrog organic 0.45 um microporous lim membrane thiab muab cov filtrate nyob rau hauv ib lub raj mis qauv xim av.

6.4 Txoj kev ntsuas

Cov kev siv tshuaj thiab cov qauv tshuaj tau raug absorbed thiab txhaj rau hauv cov kua chromatograph feem, thiab cov ntsiab lus tau txiav txim los ntawm cov txheej txheem sab nraud.

Lus Cim: Cov cuab yeej tshuaj ntawm curcumin tsis ruaj khov. Kev tswj hwm thiab cov qauv kev daws teeb meem yuav tsum raug kuaj pom hauv 2 teev tom qab kev npaj.

7 Cov txiaj ntsig suav

Cov ntsiab lus yog xam raws li formula (C1):

   (C1)

Hauv cov qauv:

AX-Tag nrho cov ncov cheeb tsam ntawm peb lub Cheebtsam nyob rau hauv lub chromatogram ntawm cov qauv tov;

Lub ncov cheeb tsam ntawm curcumin nyob rau hauv cov tshuaj chromatogram ntawm AS siv tshuaj;

C — — Cov concentration ntawm curcumin nyob rau hauv kev daws ntawm cov ntaub ntawv siv yog mg / mL;

V — — Qhov ntim ntawm cov tshuaj ntawm cov qauv, thiab chav tsev yog milliliter (mL);

M — — Qhov ntim ntawm cov qauv kuaj, thiab chav tsev yog mg.

Daim ntawv thov

● Khoom noj khoom haus additives

Turmeric extract tau ntev tau dav siv nyob rau hauv kev lag luam khoom noj khoom haus raws li ib tug nquag siv tej yam ntuj tso pigment, feem ntau yog nyob rau hauv cov xim ntawm cov kaus poom zaub mov, hnyuv khoom thiab ntses thiab marinade khoom, thiab tus nqi siv nyob rau hauv lub qub ntau lawm xav tau kev pab. Cov khoom lag luam ntawm cov khoom noj muaj txiaj ntsig nrog curcumin raws li cov khoom xyaw tseem ceeb tuaj yeem yog cov zaub mov dav dav lossis qee yam tsis yog khoom noj, xws li tshuaj ntsiav, tshuaj ntsiav lossis ntsiav tshuaj. Rau daim ntawv qhia zaub mov, qee cov khoom noj zaub mov daj tuaj yeem txiav txim siab, xws li ncuav pastries, khoom qab zib, dej haus, thiab lwm yam.

Curcumin yog cov khoom noj ntxiv uas tau pom zoo los ntawm Codex Alimentarius Commission ntawm Food and Agriculture Organization of United Nations (FAO/WHO-1995), thiab yog ib qho ntawm thawj cuaj cov xim ntuj tso cai rau siv rau hauv cov zaub mov raws li kev tshaj tawm hauv Tuam Tshoj tus qauv Hygienic rau kev siv cov khoom noj khoom haus additives.

● Chemical Indicator

Siv los ua ib qho ntsuas acid-base, pH 7.8 (daj) -9.2 (liab-xim av).

● Tshuaj

Turmeric feem ntau yog siv los ua tshuaj, thiab nws lub ntsiab bioactive Cheebtsam yog curcumin zoo li thiab volatile roj. Cov yav tas los muaj hypolipidemic, anticoagulant, antioxidant thiab choleretic teebmeem, thaum lub tom kawg mas ua raws li ib tug anti-inflammatory, antibacterial thiab hnoos suppressant.

Muaj nuj nqi:

● Alzheimer's disease

Tsiaj thwmsim ntawm Duke University tau pom tias curcumin hauv curry tsis tsuas yog rhuav tshem amyloid hauv lub hlwb ntawm lab nas, tab sis kuj tiv thaiv kev tsim cov protein no. Cov kws tshawb fawb tau sau tseg tias kev noj curry tsis tu ncua kuj tuaj yeem tsim cov teebmeem zoo sib xws rau tib neeg, yog li pab tiv thaiv Alzheimer's.

● Anti-inflammatory

Kev mob yog ib qho txheej txheem nyuaj uas tshwm sim los ntawm kev kis kab mob ntawm tes thiab / lossis cov ntaub so ntswg puas tsuaj, ua rau muaj kev cuam tshuam ntawm cov saw hlau uas thaum kawg ua rau kev loj hlob sai ntawm qee yam kab mob. Cov kev tshawb fawb tau pom tias cov tshuaj tiv thaiv kab mob ntawm curcumin extract hmoov yog piv rau cov tshuaj steroids thiab NSAIDs.

Factory & Pab Pawg:

Daim ntawv pov thawj

Ntim & Xa khoom

Cim npe nrov: Tuam Tshoj curcumin extract hmoov manufacturers, lwm tus neeg, Hoobkas