Cov khoom

Qeb khoom

Cov Khoom Kawg

Tiv Tauj Peb

6th pem teb, 2nd Building, Xijing NO.3, XiJing Industrial Park, DianZi Western Street, Xi'an, Shaanxi, Suav teb
info@gybiotech.com
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NADH hmoov

Lwm Lub Npe: Nicotinamide Adenine Dinucleotide
Cov tsos mob: Dawb mus rau yellowish hmoov
Solubility: Soluble hauv dej
Purity: Ntau dua lossis sib npaug rau 95.0%
Test Method: HPLC
Assay: Ntau dua lossis sib npaug li 95.0%
Cov ntawv pov thawj: Hala, ISO9001, PAHS Dawb, Tsis yog -GMO, KOSHER, SC
Lub sij hawm them nqi: L / C, D / A, D / P, T / TD Lub sij hawm xa tuaj: DHL, hiav txwv freight, FEDEX
MOQ: 25KGS
Pob: 25kg / Carton; 5kg / Hnab hauv
Lub sij hawm txee: Ob xyoos

Xa kev nug

Hauj lwm lawm

NADH PowderTus neeg muab khoom:

Guanjie Biotech yog NADH hmoov muag khoom. Peb tsom ntsoov rau kev muab cov khoom siv coenzyme siab -purity coenzyme siv rau hauv cov khoom noj khoom haus, lub zog- txhawb nqa, thiab cellular- cov qauv kev noj qab haus huv. Ib tus kws tshaj lij NADH cov khoom lag luam feem ntau muab NADH bulk hmoov raws li cov hmoov dawb mus rau daj daj nrog cov purity tsis tsawg dua 95.0 feem pua, txheeb xyuas los ntawm HPLC. Cov khoom yog soluble nyob rau hauv dej, tso cai yooj yim formulation rau hauv capsules, ntsiav tshuaj, dej haus, los yog cov khoom siv. Peb txhawb kev txiav txim ntau, ntim khoom raws li kev cai, thiab kev ua raws cai. Txais tos kom nug nrog peb ntawm info@gybiotech.com.

NADH Powder Supplier

COA:

Cov khoom kuaj	Specifications	Txoj Kev Xeem	Cov txiaj ntsig
Qhov tshwm sim	Dawb rau yellowish hmoov	Kev tshuaj xyuas qhov muag	Yellowish hmoov
Solubility	Soluble hauv dej	Kev tshuaj xyuas qhov muag	Soluble hauv dej
Purity	Ntau dua lossis sib npaug li 95.0%	HPLC	98.81%
Assay (lub hauv paus qhuav)	Ntau dua lossis sib npaug li 90.0%	HPLC	98.10%
Cov ntsiab lus dej	Tsawg dua lossis sib npaug li 5.0%	Karl Fischer	0.70%
Pb	Tsawg dua los yog sib npaug li 0.5 ppm	GB 5009.12	Ua raws
Raws li	Tsawg dua los yog sib npaug li 0.5 ppm	GB 5009.11	Ua raws
Hg	Tsawg dua los yog sib npaug li 0.5 ppm	GB 5009.17	Ua raws
Cd	Tsawg dua los yog sib npaug li 0.5 ppm	GB 5009.15	Ua raws
Tag nrho microbial suav	<300 CFU/g	wb 4789.2	Ua raws
E.coli	Tsis Pom	ib 4789.38	N.D.
Poov thiab pwm	<10 CFU/g	GB 4789.15	Ua raws
Salmonella	Tsis Pom	wb 4789.4	N.D.
Staphylococcus aureus	Tsis Pom	GB 4789.10	N.D.
Xaus	Ua raws li txhua qhov kev thov tshwj xeeb
Kev cia khoom:	Khaws kaw thiab qhuav, kom ntev - cia ntawm -15℃.
Kev Thauj Mus Los:	Khaws kaw, qhuav, thiab deb ntawm lub teeb rau kev thauj mus los hauv chav tsev kub.

Ua li casNADH Producted?

NADH hmoov feem ntau yog tsim los ntawm kev tsim cov txheej txheem enzymatic. Lub hom phiaj yog los hloov -NAD ( daim ntawv oxidized) rau hauv -NADH nyob rau hauv kev tswj, scalable, thiab tus nqi -txoj kev zoo thaum tuav siab purity rau kev lag luam siv. Guanjie Biotech yog -NADH cov khoom lag luam uas ua raws li cov qauv kev cai zoo rau cov ntaub ntawv ntau.

1. Raw khoom npaj

NADH hmoov Ntau lawm pib los ntawm kev npaj cov tshuaj tiv thaiv sib xyaw nrog cov khoom siv hauv qab no:

- Dej raws li cov tshuaj tiv thaiv nruab nrab.
- Enzymes uas ua rau txo qis ntawm -NAD. Cov enzymes no feem ntau yog dehydrogenases muaj peev xwm hloov cov hydrogen.
- -Nicotinamide Adenine Dinucleotide ( -NAD), lub substrate uas yuav raug txo.
- Ammonium formate, uas pub hydrogen thiab ua kom txo qis cov tshuaj tiv thaiv.

Cov khoom xyaw no ntxiv rau hauv qhov ntsuas kub thiab pH. pH feem ntau yog tswj nrog sodium hydroxide.

2. Enzyme-catalyzed hloov dua siab tshiab

Cov theem no yog qhov kev tshwm sim tseem ceeb ntawm biochemical. Lub enzyme mediates electron thiab proton hloov los ntawm hydrogen pub (feem ntau ammonium formate) mus rau -NAD. Thaum txo qis, -NAD ua -NADH. Hauv cov ntsiab lus yooj yim, enzymatic catalysis accelerates redox transformation uas yuav tshwm sim qeeb dhau hauv cov xwm txheej ib txwm muaj.

Cov txheej txheem engineers saib xyuas tus nqi tshuaj tiv thaiv, hloov xim, pH, thiab muaj peev xwm tsim cov impurities. NADH muaj cov yam ntxwv kho qhov muag pom qhov profile. Tiag - lub sijhawm saib xyuas tso cai rau tus neeg teb xov tooj los txiav txim siab thaum hloov pauv tiav yam tsis muaj kev cuam tshuam ntau dhau uas tuaj yeem oxidize cov khoom. Enzymatic biotechnology yog qhov zoo dua vim nws tsis qhia cov tshuaj hnyav, txhawb kev siv tshuaj ntsuab ntsuab, thiab muab cov khoom lag luam nrog cov bioactivity siab.

How Is NADH Produced

3. Kev tshem tawm enzyme

Tom qab hloov dua siab tshiab, enzymes yuav tsum tau muab tshem tawm kom tsis txhob muaj kab mob. Sodium hydroxide thiab pom kev pab xws li kieselguhr (diatomaceous earth) pab immobilize thiab tshem tawm cov protein seem. Kev lim dej ua kom pom tseeb cov tshuaj uas muaj -NADH.

4. Kev xav

Cov kua tseem muaj dej, ntsev, thiab ua los ntawm - khoom. Lub filtrate yog concentrated nyob rau hauv txo siab los yog kub me ntsis. Txo cov dej ntim nce ntxiv -NADH concentration thiab npaj rau kev ua kom huv.

5. Kev tshem tawm ntsev

Cov residual ammonium ions, tsis muaj ntsev, thiab tshuaj lom neeg los ntawm -cov khoom yuav tsum raug tshem tawm. Cov ntsiab lus ntsev siab txo cov crystallization kev ua tau zoo thiab qhia txog kev cia tsis ruaj khov. Kev tshem tawm ntsev tuaj yeem ua tiav los ntawm ion- pauv resins, xaiv los nag, lossis daim nyias nyias- sib cais tshuab. Desalting kuj tseem txhim kho cov xim kawg thiab txo cov kev pheej hmoo oxidation. Chemically, -NADH hmoov txhim kho cov crystallization thermodynamics, ua kom loj thiab huv si siv lead ua lattices nyob rau hauv cov kauj ruam tom ntej.

6. Secondary concentration

Tom qab desalting, cov tshuaj ntxiv yog concentrated dua. Lub hom phiaj yog kom ncav cuag supersaturation, qhov twg cov tshuaj muaj ntau yaj -NADH dua li nws muaj peev xwm tuav nyob rau hauv equilibrium. Supersaturation yog qhov tseem ceeb rau kev ua tiav crystallization. Cov kws kho mob saib xyuas pH vim tias oxidation hloov pauv -NADH rov qab mus rau -NAD. Nitrogen pam los yog qis-Oxygen ib puag ncig tau ua haujlwm hauv ntau lub hoobkas.

7. Crystallization siv ethanol

Crystallization yog ib qho tseem ceeb purification theem. Ethanol tau nkag mus rau hauv cov tshuaj muaj zog vim tias NADH hmoov tau txo cov solubility hauv hydro- dej cawv sib tov. Thaum cov ntsiab lus ethanol nce, -NADH pib nucleate thiab tsim cov muaju. Kev tswj cov cua txias ua kom cov nyhuv no thiab ua rau cov khoom sib xws morphology.

Crystal zoo cuam tshuam rau flowability, xim stability, thiab downstream drying cwj pwm. Yog li ntawd, crystallization yuav txo tau qhov kub thiab txias, tswj ethanol dosing, thiab tswj agitation los tiv thaiv amorphous nag lossis daus.

8. Centrifugation

Thaum crystallization ncav cuag kev loj hlob, lub centrifuge yog siv los cais cov khoom -NADH crystals los ntawm niam cawv. Centrifugation muab siab dhau, lub sijhawm ua haujlwm luv luv, thiab tsawg kawg oxidation raug piv rau lub ntiajteb txawj nqus pom. Cov cawv niam feem ntau muaj cov seem -NADH thiab tuaj yeem siv rov ua dua, txhim kho cov khoom tsim tawm thiab kev lag luam.

9. Qhuav

Cov pob zeb ntub dej yog qhuav kom tshem tawm cov dej noo. Vim -NADH hmoov yog rhiab heev rau oxidation thiab UV teeb, tiv thaiv kom qhuav txoj kev siv. Cov no suav nrog lub tshuab nqus tsev ziab, ncig hauv qab nitrogen, lossis qis- tshuab ziab khaub ncaws kub. Thaum tshav kub kub heev yuav ua rau lub redox functionality. Kev txo cov dej noo kom ruaj khov thiab ua kom lub neej ntev.

Kev ziab kawg yog txiav txim siab los ntawm kev ntsuas dej noo, vim tias cov dej ntxiv tuaj yeem ua kom hydrolysis thiab xim degradation.

10. Ntim

Thaum kawg, NADH hmoov tau ntim rau hauv lub teeb - tiv thaiv, oxygen- cov thawv txwv. Aluminium foil hnab los yog nitrogen-flushed fwj muaj ntau. Kev ntim khoom kom zoo tiv thaiv kev hloov pauv rov qab mus rau -NAD thiab txuas ntxiv lub neej cia.

Txoj kev enzymatic tau txais txiaj ntsig vim nws zam cov tshuaj hnyav, tswj kev ua haujlwm bioactivity, thiab txhawb nqa siab -purity tso zis xav tau rau kev tshawb fawb reagents, coenzyme tshuaj, cov khoom xyaw tshuaj, thiab cov khoom siv biochemical. Kev ua lag luam yuav tsum muaj kev tswj xyuas kom zoo rau purity, noo noo, microbial load, thiab lub cev ruaj khov.

Guanjie Biotech yog NADH cov khoom lag luam muab cov khoom lag luam ntau- qib nrog rau kev tsom mus rau purity, sib xws, thiab tus nqi sib tw rau cov neeg yuav khoom lag luam.

NADH yog dab tsi Chemical Sqauv?

• Core Molecular Framework

NADH hmoov yog daim ntawv txo qis ntawm nicotinamide adenine dinucleotide, thiab nws cov qauv tshuaj yog tsim los ua dinucleotide. Nws muaj ob nucleotides koom nrog lawv pawg phosphate. Ib qho nucleotide nqa lub hauv paus adenine, thaum lwm tus yog nicotinamide puag. Txhua nucleotide suav nrog ribose qab zib, thiab tus choj pyrophosphate txuas ob chav ribose. Qhov ntau- cov txheej txheem txheej txheem no ua rau NADH loj, muaj kev sib koom ua ke coenzyme ntau dua li qhov yooj yim me me molecule.

• Nicotinamide Nplhaib thiab Redox Function

Cov nicotinamide feem yog hloov pauv pyridine nplhaib uas ua lub luag haujlwm tseem ceeb redox. Hauv nws daim ntawv oxidized (NAD⁺), lub nplhaib yog electron -tsis muaj. Thaum nws txais hydride ion (H⁻), nws dhau los ua NADH. Cov tshuaj tiv thaiv no ntxiv ob lub tshuab hluav taws xob thiab ib qho proton rau lub nplhaib, hloov nws cov qauv hluav taws xob thiab ua kom nws pub cov khoom siv hluav taws xob hauv cov tshuaj tiv thaiv metabolic tom qab. Lub nplhaib nicotinamide txo qis yog dab tsi muab NADH hmoov nws lub peev xwm los koom nrog hauv lub zog metabolism, tshwj xeeb hauv txoj hauv kev xws li glycolysis, TCA voj voog, thiab mitochondrial electron thauj.

• Adenine Nucleotide thiab Structural Stability

Sab adenine ntawm NADH muaj cov purine puag txuas nrog ribose qab zib thiab phosphate pawg. Txawm hais tias adenine tsis ua cov tshuaj tiv thaiv redox, nws muab cov qauv thauj tog rau nkoj uas pab cov enzymes paub thiab khi NADH. Enzymes koom nrog hauv cov tshuaj tiv thaiv dehydrogenation feem ntau muaj cov hnab ris uas cuam tshuam nrog adenine ribose thiab tus choj pyrophosphate. Lub cheeb tsam ntawm cov molecule no ua kom muaj kev taw qhia zoo ntawm lub nplhaib nicotinamide rau kev hloov hluav taws xob zoo.

• Peb-Kev Ua Raws Cai

NADH hmoov muaj qhov hloov pauv peb - qhov sib txawv, tso cai rau nws los kho nws cov duab thaum khi cov enzymes sib txawv. Cov molecule tuaj yeem khoov ib ncig ntawm pyrophosphate linkage, ua rau lub nplhaib nicotinamide mus txog qhov chaw catalytic thaum cov adenine feem tseem nyob hauv thaj tsam khi. Qhov kev hloov pauv ntawm cov qauv no txhawb nqa NADH txoj haujlwm ua tus cab hluav taws xob txawb. Los ntawm kev kaw cov electrons hla txoj hauv kev metabolic, NADH pab tsim ATP thiab tswj lub zog ntawm tes.

How uarauNADHhmoov khoom?

Ib lub tuam txhab uas muab NADH hmoov yuav tsum tswj peb lub peev xwm tseem ceeb: kev muab khoom, kev tswj kom zoo, thiab cov neeg siv khoom- sab kev txhawb nqa. NADH hmoov yog ib daim ntawv txo thiab ruaj khov ntawm NMN, tsim los xa cov khoom siv roj ntsha ntau dua thiab zoo dua NAD+- txhawb nqa kev ua tau zoo dua li tus qauv NMN. Vim li no, tus neeg muag khoom yuav tsum kho nws raws li qib siab - tus nqi, siab - rhiab heev nutraceutical muaj.

Kev ruaj ntseg ntseeg tau ntau lawm

Ua ntej, tus neeg muag khoom txo qis nicotinamide mononucleotide yuav tsum muaj kev ruaj ntseg ntau lawm. NADH tuaj yeem tsim los ntawm kev siv tshuaj lom neeg lossis cov txheej txheem lom neeg. Ob txoj hauv kev yuav tsum tau tswj cov khoom siv raw, cov txheej txheem tshuaj tiv thaiv zoo, thiab cov tshuab ua kom huv uas tshem tawm cov kuab tshuaj seem thiab impurities. Tus neeg muag khoom ib txwm ua kev tsim khoom hauv GMP-cov chaw ua haujlwm kom huv si, taug qab, thiab cov ntaub ntawv. Kev ruaj ntseg thev naus laus zis yog qhov tseem ceeb vim tias NADH muaj oxygen ntau dua -sensitive dua NMN. NADH hmoov cov chaw muag khoom feem ntau siv qis - ntim cov pa oxygen, nitrogen flushing, thiab txias -chain warehousing los khaws cia lub xeev txo ntawm cov molecule.

Analytical Quality

Qhov thib ob, NADH cov khoom lag luam yuav tsum ua kom pom qhov zoo tshaj plaws. Reputable Nicotinamide Adenine Dinucleotide hmoov yog txheeb xyuas los ntawm HPLC los yog UPLC kom paub meej tias purity, feem ntau yog tsom rau 98 feem pua lossis siab dua. Cov kev ntsuam xyuas ntxiv yuav suav nrog cov hlau hnyav, cov khoom siv microbial, cov kuab tshuaj seem, thiab kev txheeb xyuas tus kheej siv MS lossis NMR. Daim ntawv pov thawj ntawm Kev Ntsuam Xyuas yuav tsum tau muab rau txhua pawg, thiab ua raws li HALAL, KOSHER, thiab ISO systems txhim kho kev ntseeg siab ntawm cov neeg xa khoom rau cov neeg yuav khoom thoob ntiaj teb.

Txhawb nqa Formulation Cov neeg siv khoom

Thib peb, NADH hmoov cov neeg muag khoom yuav tsum txhawb nqa cov neeg siv khoom hauv qab. Nutraceutical hom, cov tuam txhab tshuaj ntsiav, thiab cov tuam txhab dej haus ua haujlwm xav tias yuav muaj kev qhia txog kev solubility, cov ntaub ntawv ruaj khov, pom zoo ntau npaum li cas, cov ntawv tswj hwm, thiab cov lus qhia ntim. Vim hais tias NMNH yog rhiab heev rau oxidation, tus neeg muag khoom yuav tsum qhia cov neeg muas zaub txog excipient compatibility, pH raug, thiab cia kub.

Supply Reliability

Thaum kawg, kev ntseeg siab ntawm cov khoom siv yog qhov tseem ceeb. Ib qho kev sib tw NADH hmoov cov khoom lag luam tswj cov khoom muag, muab cov kilogram- theem khoom xa tuaj, txhawb nqa cov ntaub ntawv xa tawm, thiab muab cov nqi sib tw. NADH cov khoom lag luam ntau tus nqi lag luam tsis yog xa cov hmoov xwb tab sis ua kom muaj kev ua tau zoo los ntawm kev tsim khoom los ntawm qhov kawg - siv daim ntawv thov.