lus 98

Apigenin 98 Tus neeg muab khoom:

Guanjie qhov zoopib 98- ib lub teeb daj hmoov. Nws yog yuav luag insoluble nyob rau hauv dej, ib nrab soluble nyob rau hauv kub cawv, soluble nyob rau hauv dilute KOH kua. Siab zoo thiab tus nqi sib tw. Peb muaj kev paub zoo tshaj plaws los xyuas kom meej qhov zoo. Txhawm rau kom ntseeg tau qhov zoo, peb tuaj yeem muab peb tus kheej kuaj HPLC daim ntawv tshaj tawm thiab kev kuaj thib peb. Muaj 2 cov kab tsim tawm hauv peb lub tuam txhab thiab peb tuaj yeem tsim nws txog 20 tons hauv ib xyoos. Peb tam sim no muaj ntau tshaj 50 tus neeg muas zaub los ntawm teb chaws USA, EU, Southeast Asia, thiab hais txog.

 

Vim li cas thiaj xaiv Guanjie?

● GMP tus qauv rhiav thiab ob lub chaw soj nstuam ywj pheej, uas ua kom muaj kev tswj xyuas zoo thiab cov khoom purity.

● Peb muaj ob lub chaw soj nstuam ywj pheej, uas tso cai rau kev sim thiab tshuaj xyuas ntawm peb cov khoom kom ntseeg tau tias lawv ua tau raws li qhov purity thiab kev ua tau zoo.

● Muaj kev sib koom tes muaj zog: Northwestern University thiab Suav Academy ntawm Sciences chaw tshawb fawb.

● Kev tswj xyuas nruj nruj: Yuav luag tag nrho cov khoom siv kuaj cov khoom kuaj hauv tsev. qhov kev ntsuam xyuas, dej, ntxhiab, cov hlau hnyav, Cov Khoom Siv Hluav Taws Xob, cov tshuaj tua kab residue, Protein, Microbiological, thiab lwm yam.

● Kev xa khoom xa tuaj: Cov kws tshaj lij kev xa khoom tau koom tes nrog peb rau ntau tshaj 20 xyoo, xyuas kom meej tias cov khoom tuaj yeem raug xa tawm sai thiab nyab xeeb.

 

Khoom Taw Qhia:

Apigenin yog flavonoid compound dav dav hauv cov nroj tsuag lub nceeg vaj. Nws ua raws li cov dawb radical scavenger thiab antioxidant, txo oxidative kev nyuaj siab. Nws yog ib hom glycoside, uas yog hais txog cov molecule uas txuas nrog cov suab thaj molecule. Flavonoids yog ib chav kawm ntawm phytochemicals uas tshwm sim nyob rau hauv cov ntaub so ntswg. Lawv ua lub luag haujlwm tiv thaiv cov nroj tsuag tiv thaiv kab mob thiab hnub ci hluav taws xob. Lawv kuj pab nyiam pollinators thiab tswj cov nroj tsuag metabolism.

 

COA:

 

Flow Chart:

 

Specifications:

● Cov tsos: Zoo, lub teeb daj hmoov
● Solubility:

Nws yog me ntsis soluble nyob rau hauv dej, soluble nyob rau hauv cawv solvents xws li ethanol thiab methanol, thiab insoluble nyob rau hauv non-polar solvents xws li hexane thiab chloroform.
● Purity:

Guanjie's Apigenin 98 hmoov muaj purity ntawm 98 feem pua ​​lossis siab dua. Thiab peb tuaj yeem txhawb cov khoom customized.
● Lub neej txee:

Thaum khaws cia rau hauv qhov chaw txias, qhuav, nws muaj lub neej txee ntawm kwv yees li ob xyoos.

 

Puas yog Apigenin Safe?
Apigenin belongs rau flavonoid subclass ntawm polyphenolic tebchaw thiab yog cov tsis muaj tshuaj lom, tsis-mutagenic noj flavonoid. Raws li kev tshawb fawb, cov nroj tsuag ntuj uas muaj cov ntsiab lus apigenin siab muaj txog 200 ug txog 500 ug / g, thiab cov nyiaj no yog ob npaug ntawm cov khoom qhuav.

 

Apigenin cuam tshuam li cas rau cov txheej txheem ntawm kev kis tus kab mob?
Txawm hais tias kev txhaj tshuaj tiv thaiv yog lub tswv yim tseem ceeb los tiv thaiv tus kab mob khaub thuas, vim qhov kev hloov pauv ntawm tus kab mob khaub thuas ntau heev, tus kab mob no feem ntau tuaj yeem zam qhov kev tiv thaiv no. Yog li, cuam tshuam nrog kev rov ua dua ntawm tus kab mob thaum lub sijhawm kis kab mob tuaj yeem yog qhov kev cog lus tshiab rau kev mob khaub thuas. Apigenin tau pom tias inhibit qhov kev rov ua dua ntawm tus kab mob khaub thuas thiab lwm yam kab mob.

 

Muaj nuj nqi:
●Inhibits IAV-induced activation ntawm RIG-I thiab cell tuag.

Thaum kis tus kab mob khaub thuas A virus (IAV), apigenin inhibits qhov kev qhia ntawm RIG-I thiab kev tsim cov dej ntws qis IFN thiab cytokines. Txawm hais tias RIG-I yog ib qho tseem ceeb innate RNA sensor uas paub txog IAV RNA genome, activates tus tswv teb antiviral teb, thiab amplifies lub cytokine cascade uas ua rau kom tiv thaiv IAV kab mob, overproduction ntawm IFN thiab inflammatory cytokines tuaj yeem ua rau mob IAV mob thiab immunopathological. mob ntsws. Apigenin tuaj yeem tiv thaiv IAV-induced cell tuag.

 

● Txhawb ubiquitin-mediated RIG-I protein degradation.
Apigenin 98 tsis muaj kev cuam tshuam rau kev sib cuam tshuam ntawm RIG-I thiab 3pRNA, yog li nws tsis tsom rau lub teeb liab qis ntawm RIG-I tab sis ncaj qha lub hom phiaj RIG-I. Cov kev tshawb pom pom tau hais tias apigenin inhibits kev ua haujlwm ntawm RIG-I txoj kev taw qhia tej zaum los ntawm kev cuam tshuam nrog nws cov kev cuam tshuam nrog Hsp90 thiab txhim kho nws cov kev cuam tshuam nrog RNF125, ua rau muaj zog ubiquitin-mediated degradation ntawm RIG-I protein.

 

●Inhibits IAV replication thiab viral NA kev ua si.
RIG-I yog ib qho tseem ceeb ntawm tus kab mob RNA sensor uas ua rau lub cev tiv thaiv kab mob hauv lub cev thiab yog qhov tseem ceeb rau tus tswv tsev tiv thaiv tus kab mob khaub thuas. Txawm hais tias apigenin inhibited IAV-induced activation ntawm RIG-I, nws muaj kev tiv thaiv kab mob tiv thaiv IAV hauv vitro. Cov txiaj ntsig tau pom tias apigenin tsis muaj qhov cuam tshuam rau tus kab mob nkag mus thiab tom qab kis kab mob genome replication thaum lub sij hawm ib lub voj voog kab mob (8 teev ua ntej).

 

Txawm li cas los xij, nws tuaj yeem cuam tshuam tus kab mob sib dhos thiab tso tawm, yog li cuam tshuam rau ntau lub voj voog kab mob (los ntawm 8 txog 48 teev). Lwm txoj kev tshawb fawb tau tshaj tawm tias apigenin cuam tshuam rau NA kev ua haujlwm ntawm IAV raws li kev noj tshuaj thiab tuaj yeem cuam tshuam tus kab mob rov ua dua tshiab.

 

Risks thiab Side Effects:
Apigenin 98 raug suav hais tias muaj kev nyab xeeb thaum noj ntau npaum li cas los ntawm kev noj zaub mov uas muaj txiv hmab txiv ntoo, zaub, thiab tshuaj ntsuab. Yog tias koj muaj mob plab tom qab noj chamomile extract, qee zaum vim nws qib siab ntawm apigenin, txiav siv tam sim ntawd.
Cov tshuaj pleev xim uas muaj cov khoom noj no tuaj yeem ua rau tawv nqaij khaus ntawm qee tus neeg, yog li tsis txhob siv cov khoom no yog tias koj muaj kev phiv tshuaj.
Kev tshawb fawb ntxiv yog xav tau kom nkag siab txog kev nyab xeeb ntawm cov koob tshuaj apigenin siab. Nrog koj tus kws kho mob tham ua ntej siv cov tshuaj los yog tshuaj ntxiv los kho tus mob.

 

Factory & Pab Pawg:

 

Daim ntawv pov thawj

 

Ntim & Xa khoom

Cim npe nrov: Tuam Tshoj apigenin 98 manufacturers, lwm tus neeg, Hoobkas