Ntau Ergothioneine

Bulk Ergothioneine Supplier:

Guanjie Biotech muab cov khoom zoontau ergothioneine. Peb siv fermentation thiab biosynthetic txoj kev los tsim ergothioneine tej hmoov. Kev soj ntsuam ntawm peb cov khoom tuaj yeem ncav cuag ntau dua 98%. Peb siv txoj kev kuaj HPLC. Yog tias koj cuam tshuam nrog peb cov khoom lossis sab laj nrog peb tus nqi ergothioneine, peb tuaj yeem muab cov qauv dawb rau koj thiab kuaj cov qauv. Txais tos nug peb:info@gybiotech.com.  

 

COA:

Yam khoom	Specification	Txoj kev analytical
Qhov tshwm sim	Tawm dawb mus rau dawb hmoov zoo	Pom kev
Kev txheeb xyuas	Qhov zoo	IR & 1H NMR
Assay (Rau lub hauv paus qhuav)	Ntau dua lossis sib npaug rau 98.0%	HPLC
Poob rau ziab	Tsawg dua lossis sib npaug rau 1.0%	USP
Residue ntawm ignition	Tsawg dua lossis sib npaug rau 5.0%	USP
Cov hlau hnyav	Tsawg dua lossis sib npaug li 10 ppm	ICP-MS
Arsenic	Tsawg dua lossis sib npaug li 2 ppm	ICP-MS
Coj	Tsawg dua lossis sib npaug li 1ppm	ICP-MS
Mercury	Tsawg dua lossis sib npaug li 2 ppm	ICP-MS
Tag nrho cov kab mob suav	Tsawg dua lossis sib npaug li 10000 CFU / g	AOAC
Pwm thiab Poov xab	Tsawg dua lossis sib npaug li 300 CFU / g	AOAC
Escherichia coli 10 g	Tsis muaj / 10g	AOAC
Staphylococcus aureus 10g	Tsis muaj / 10g	AOAC
Salmonella 25 g	Tsis muaj / 25g	AOAC
Pseudomonas Aeruginosa 25g	Tsis muaj / 25g	AOAC

 

Kev nyab xeeb:

Nyob rau hauv cov ntaub so ntswg noj qab haus huv, ergothioneine siv cov tshuaj tua kab mob antioxidant yam tsis cuam tshuam nrog ROS / RNS kev ua. Thaum oxidative kev puas tsuaj loj heev, ergothioneine accumulates ntau nyob rau hauv lub cev nqaij daim tawv thiab exerts antioxidant teebmeem. Tib neeg cov kev tshawb fawb qhia tias ergothioneine tuaj yeem ua feem ntau nyob rau hauv cov xwm txheej ntawm oxidative kev nyuaj siab. Ergothioneine yog ib qho muaj zog antioxidant. Piv rau lwm cov tshuaj antioxidants ntuj,ntau ergothioneinemuaj qhov zoo hauv qab no:

• nqus qhov ncauj sai. Qhov no tso cai rau kom muaj kev faib tawm ntawm cov chaw nkag siab rau oxidative kev nyuaj siab, qeeb metabolism, thiab cov teebmeem ntev.

• Nws muaj kev ua haujlwm antioxidant siab hauv lub cev ib puag ncig thiab tsis txhawb Fenton cov tshuaj tiv thaiv.

• Ergothioneine hmoov tsis yooj yim oxidized thiab muaj qhov zoo tshaj plaws thermal thiab pH stability.

• Ergothioneine bulk hmoov muaj kev nyab xeeb zoo. Nws accumulates nyob rau hauv high concentrations nyob rau hauv cov ntaub so ntswg yam tsis tau soj ntsuam toxicity.

Cov kev tshawb fawb tsiaj tau pom tias ERG kuj muaj lwm yam kev ua ub no lom neeg. Nws suav nrog lub peev xwm los tiv thaiv UV-induced photodamage thiab melanosis los ntawm tib neeg daim tawv nqaij. Nws tuaj yeem tiv thaiv menyuam qaib los ntawm glucocorticoid-induced cataract puas, tiv thaiv daim siab, hnyuv, thiab raum.

Tsis tas li ntawd, bulk L-EGT aqueous tov muaj cov khoom noj zoo khaws cia. Cov kev tshawb fawb tau pom tias kev kho mob tom qab sau qoob Agaricus bisporus nceb nrogntau ergothioneinetshuaj slows down browning thiab extends txee lub neej. L-EGT aqueous kua muab rho tawm los ntawm cov nceb enoki tuaj yeem siv los tiv thaiv kev tsim cov hlau hemoglobin siab hauv cov nqaij tuna thiab ua kom nws cov xim ci. Nyob rau hauv qhov kub thiab txias, L-EGT-nplua nuj nceb extracts inhibited lipid oxidation nyob rau hauv salmon nqaij cov ntaub so ntswg.In 2016, lub European Union tau tshaj tawm kev nyab xeeb rau L-EGT raws li ib tug khoom noj additive, ntxiv broaden txoj kev rau daim ntawv thov ntawm L- EGT hmoov hauv kev txuag zaub mov thiab freshness.

 

Txog niaj hnub no, tsis muaj kev phiv tshwm sim hauv kev kawm toxicology kev tshawb fawb ntawmFeem ntau ergothioneine. Muaj pov thawj los ntawm pej xeem kev cuam tshuam kev tshawb fawb ntawm EGT qhia tias EGT yog tus cim kev ywj pheej ntawm kev pheej hmoo tsawg ntawm cov kab mob cardiometabolic thiab kev tuag. Kev noj ntau ntxiv ntawm EGT-nplua nuj nceb cov khoom noj muaj txiaj ntsig zoo nrog kev paub txog kev ua haujlwm zoo dua thiab nrog qis qis ntawm kev paub tsis meej me ntsis. Kev siv tsis zoo ntawm EGT tsis tau tshaj tawm.

 

Daim ntawv thov:

Ergothioneine raws li ntuj amino acid nrog antioxidant zog.Feem ntau ergothioneinemuaj ntau yam muaj peev xwm siv hauv kev lag luam zaub mov. Cov hauv qab no yog cov kev siv ntawm ergothioneine hmoov nyob rau hauv cov khoom noj additives:

● Khoom noj khoom haus noj qab haus huv

Ergothioneine tau ntxiv rau ntau yam khoom noj khoom haus kev noj qab haus huv vim nws cov khoom antioxidant.Lub Xya hli ntuj 2017, European Union tau tshaj tawm txoj cai 2017/1281, uas tau pom zoo ergothioneine ua cov khoom noj khoom haus tshiab. Nws kuj teev cov txheej txheem tshwj xeeb, cov ntsiab lus hlau hnyav, cov txheej txheem microbiological, thiab siv cov kev txwv ntxiv rau cov khoom noj.

● Khoom noj khoom haus

Ergothioneine kuj tseem siv rau hauv cov khoom noj khoom haus. Nws tuaj yeem pab tib neeg cov ntaub so ntswg nrog antioxidant, tiv thaiv inflammatory, inhibit hnyav hlau toxicity, tiv thaiv lub hlwb los ntawm neurotoxins, tiv thaiv kev txawj ntse poob, thiab lwm yam.

● Khoom noj khoom haus

EU nthuav dav kev siv ergothioneine hauv 2018. Nws tuaj yeem siv rau hauv cov dej qab zib, cereal bars, thiab lwm yam khoom noj khoom haus ntxiv rau kev noj haus.

● Cov khoom xyaw tshuaj pleev ib ce

Daim ntawv thov ntawmntau ergothioneinenyob rau hauv tshuaj pleev ib ce tau kuj mature. Txawm li cas los xij, nrog kev txhim kho ntawm kev ua lag luam, raws li "tiam tshiab" ntawm cov khoom xyaw ua haujlwm, ergothioneine tau tsim ntau tus qauv hauv kev siv tshuaj pleev ib ce.

● Khoom noj khoom haus additives

Ergothioneine bulk hmoov tuaj yeem siv los ua cov khoom noj ntxiv los txhim kho cov khoom noj muaj txiaj ntsig ntawm cov zaub mov thiab ua kom lub neej ntev. Nws cov khoom antioxidant pab tiv thaiv cov zaub mov los ntawm kev puas tsuaj oxidative thiab tswj qhov tshiab thiab xim ntawm cov zaub mov.

 

Ntiaj teb no Regulatory Status ntawm Ergothioneine

1. Teb Chaws Asmeskas

• Nyob rau xyoo 2011, Oxis International Inc. tshaj tawm tias nws cov ntshiab L-ergothioneine, uas tsim los siv ib tug tswv cuab ntawm cov tshuaj synthesis txoj kev, tau raug lees paub los ntawm ib tug ywj siab vaj huam sib luag ntawm scientific kws txawj raws li muaj GRAS (feem ntau lees paub tias muaj kev nyab xeeb).Feem ntau ergothioneinetuaj yeem siv tau thiab noj ua zaub mov nrog Kev Txais Txhua Hnub (ADI) ntawm 10.5mg / d. Nws yog tib lub tuam txhab lag luam thaum lub sijhawm tsim cov khoom noj khoom haus uas siv cov ntshiab L-ergothioneine.

• Paris, Fabkis-based Tetrahedron tshaj tawm thaum Lub Ob Hlis 2015 tias nws cov khoom lag luam ergothioneine tau dhau qhov kev ntsuam xyuas GRAS ywj pheej.

• Xyoo 2018, US FDA tau lees paub GRAS xwm txheej ntawm ergothioneine tsim los ntawm Blue Califonia siv cov kab mob genetic engineered rau fermentation. Nws tuaj yeem siv rau hauv ncuav mog qab zib, ncuav qab zib thiab pastries (xws li granola bars), kas fes, tshuaj yej, txiv hmab txiv ntoo haus thiab cider, carbonated dej qab zib, thiab confectionery muaj chocolate. Nws yog siv nyob rau theem ntawm 5 mg / pab.

 

2. Teb chaws Europe.

• Hauv xyoo 2016, EFSA tau txais kev soj ntsuam kev nyab xeeb Novel Food (NF) rau ergothioneine. Qhov kev ntsuam xyuas no tau xaus lus tias cov khoom siv hluavtaws L-ergothioneine muaj kev nyab xeeb rau kev siv hauv cov dej haus uas tsis muaj cawv, cereal tuav, mis nyuj, cov khoom siv mis nyuj tshiab thiab cov qhob noom xim kasfes ntawm qhov siab tshaj plaws ntawm 5 mg ib zaug. Cov zaub mov tshiab tuaj yeem siv los ua kev noj haus ntxiv. Cov koob tshuaj txhua hnub yuav tsum tsis pub tshaj 30 mg / hnub rau cov neeg laus thiab 20 mg / hnub rau menyuam yaus. Cov pej xeem npaj yog cov menyuam yaus hnub nyoog qis dua 3 xyoos thiab cov neeg laus feem ntau, tshwj tsis yog cov poj niam cev xeeb tub thiab lactating.

• Hauv xyoo 2017 EFSA tau lees paub ntxiv tias qhov kwv yees tau txais txhua hnub ntawm ergothioneine sib raug rau cov kev pom zoo yav dhau los yog 2.82 mg / kg lub cev hnyav (bw) rau cov menyuam mos thiab 3.39 mg / kg bw rau cov menyuam yaus. Cov neeg laus suav nrog cov poj niam cev xeeb tub thiab lactating 1.31 mg / kg bw. Nyob rau theem no additive, hluavtawsntau ergothioneinemuaj kev nyab xeeb.

• Nyob rau hauv 2018, European Commission ((EU) 2018/462) pom zoo hluavtaws L-ergothioneine rau siv nyob rau hauv cov zaub mov. Nws tuaj yeem muab ntxiv rau cov dej tsis muaj cawv thiab mis nyuj haus ntawm 0.025g / kg, cov khoom noj mis nyuj tshiab ntawm 0.04g / kg, cereal bars ntawm 0.2g / kg, chocolate confectionery ntawm 0.25g / kg, thiab noj tshuaj ntxiv rau cov neeg uas tsis yog cov poj niam cev xeeb tub thiab cov niam cev xeeb tub ntawm 30mg / hnub, thiab rau cov menyuam hnub nyoog 3 xyoos thiab siab dua ntawm 20mg / hnub.

 

3. Lwm lub teb chaws thiab cheeb tsam

• Kev tshawb nrhiav lo lus "ergothioneine" ntawm lub vev xaib ntawm Health Canada tsis tau txais txiaj ntsig ntsig txog kev noj zaub mov ntxiv.

• Kev tshawb nrhiav lo lus "ergothioneine" ntawm lub vev xaib ntawm Food Standards Australia New Zealand (FSANZ) tsis muaj txiaj ntsig cuam tshuam txog kev tswj hwm kev noj zaub mov ntxiv.

• Kev tshawb nrhiav "ergothioneine" ntawm lub vev xaib ntawm Ministry of Health thiab Ministry of Health thiab Welfare ntawm Nyiv, FDA ntawm Philippines, Agri-Food thiab Veterinary Authority (AVA) ntawm Singapore, thiab FDA ntawm Taiwan tau txais txiaj ntsig. tsis muaj kev tswj xyuas cov txiaj ntsig rau nws siv los ua zaub mov ntxiv.

 

Kev ua lag luam:

Tam sim no,ntau ergothioneinetau paub txog kev txhim kho hla ciam teb hauv tshuaj pleev ib ce, khoom noj khoom haus, khoom noj khoom haus thiab biopharmaceutical industries, thiab lwm yam. QYResearch kev tshawb fawb qhia tau hais tias lub ntiaj teb no ergothioneine lag luam loj yuav yog li ntawm 130 lab yuan nyob rau hauv 2021, thiab xav kom ncav cuag 1.1 billion yuan nyob rau hauv 2028, uas qhia tau hais tias. hais tias txoj kev loj hlob prospect yog zoo heev. Nws xav tias yuav ncav cuag 1.1 billion nyiaj hauv 2028. Nws tuaj yeem pom tias qhov kev cia siab ntawm kev loj hlob yog qhov dav heev.

Ntawm lawv, tshuaj pleev ib ce yog ib qho ntawm feem ntau siv teb ntawmbulk ergothioneine hmoov. Tebchaws Asmeskas thiab Europe yog cov lag luam loj tshaj plaws rau kev siv EGT. Lawv suav hais tias EGT yog lub thib tsib tiam antioxidant, uas yog siv nyob rau hauv txhua yam ntawm cov tshuaj pleev ib ce loj. Nyob rau hauv Suav teb, EGT tau teev nyob rau hauv phau ntawv teev cov khoom siv tshuaj pleev ib ce los ntawm yav dhau los Lub Xeev Food and Drug Administration txij li xyoo 2014, uas tau txhawb nqa kev tshawb fawb thiab kev siv EGT los ntawm cov tuam txhab tshuaj pleev ib ce.

 

Factory & Pab Pawg:

 

Daim ntawv pov thawj

 

Ntim & Xa khoom

Cim npe nrov: Tuam Tshoj bulk ergothioneine manufacturers, lwm tus neeg, Hoobkas