Carob Seed Extract hmoov

Carob Noob ExtractPowder Supplier:

Guanjie Biotech yog Carob Seed Extract Powder tsum. Peb D－Pinitol hmoov yog los ntawm cov taum ntuj carob uas loj hlob raws ntug dej hiav txwv Mediterranean. Peb muab 95% -98% D-Pinitol. Siab zoo thiab tus nqi sib tw. Txais tos kom nuginfo@gybiotech.com.

COA:

Yam khoom	Specification	Kev tshwm sim	Method
Cov ntaub ntawv tseem ceeb ntawm cov khoom
Lub Tebchaws Keeb Kwm	Tuam Tshoj	Ua raws	/
Marker Compounds
D - Pinitol (nyob rau hauv qhuav hauv paus)	>98.0%	99.31%	HPLC
Cov ntaub ntawv Organoleptic
Qhov tshwm sim	Hmoov	Ua raws	NLS-QCS-1008
Xim	Dawb hmoov	Ua raws	GB/T 5492-2008
tsw	Yam ntxwv	Ua raws	GB/T 5492-2008
Saj	Yam ntxwv	Ua raws	GB/T 5492-2008
Cov ntaub ntawv txheej txheem
Txoj kev ua	Kev rho tawm	Ua raws	/
Solvent(s) siv	Ethanol & Dej	Ua raws	/
Txoj Kev Qhuav	Nqus kom qhuav	Ua raws	/
Excipient	Tsis muaj	Ua raws	/
Cov yam ntxwv ntawm lub cev
Melting point	178-185 degree	180-185 degrees	GB21781-2008T
Specific Optical Rotation	NLT ﹢ 55 degree	Qhov ntsuas kub ntawm qhov ntsuas kub yog 60.1 degree	Ib 613-88
Particle Loj (40 mesh)	98.0% dhau 40 mesh	Ua raws	GB/T 5507-2008
Poob rau ziab	<1.5%	0.52%	GB/T 14769-1993
Tshauv Ntsiab Lus	<1.5%	0.41%	AOAC 942.05, 18
Solvent Residue	Ethanol	Ua raws	NLS-QCS-1007
Hnyav Hlau
Total Heavy Metals	<10 ppm	Ua raws	USP<231>, method II
Arsenic	<2.0 ppm	Ua raws	AOAC 986.15, 18
Tshuaj tua kab
666	<0.2ppm	Ua raws	GB/T5009.19-1996
DDT	<0.2ppm	Ua raws	GB/T5009.19-1996
Microbiology
Tag Nrho Phaj suav	<1000/g	37/g	AOAC 990.12, 18
Total Poov & Pwm	<100/g	<9/g	FDA (BAM) Tshooj 18, 8th Ed.
E. Coli	Tsis zoo	Tsis zoo	AOAC 997.11, 18
Salmonella	Tsis zoo	Tsis zoo	FDA (BAM) Tshooj 5, 8th Ed.

 

Flow Chart:

Amicogen covcarob uasua edextracthmoovD-Pinitol yog tsim los raws li Kev Tswj Xyuas Zoo (GMP) tau pom zoo los ntawm Kaus Lim Kauslim Khoom Noj thiab Tshuaj / Kev Tswj Xyuas.

Extraction ntawm carob taum pod nrog dej

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Hydrolysis ntawm extract

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Lim thiab nqus concentration

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Kev sib cais nrog ib kab hluav taws xob

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Lub tshuab nqus tsev concentration

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De-salting nrog ion exchanges

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Membrane filtration thiab nqus concentration

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Crystallization

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Qhuav thiab sib tsoo

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Ntim

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D-Pinitol

Pinitol cov ntsiab lus tsom xam

1) Machinery: HPLC (Kev ua haujlwm siab ua kua chromatography)

2) Kev Npaj Carob Seed Extract Powder Standard tov: Ua qhov kawg ntim 100 los ntawm kev ntxiv 50% Acetonitrile ntawm carob noob extract D-pinitol hmoov txheem 1g. Tus qauv hnyav yog lim qhov no los ntawm 0.45 μm membrane lim.

3) Test hnyav: Test hnyav yog ua raws li tus qauv hnyav ua.

4) Kev soj ntsuam

HPLC mob

Cov ntawv	Cov xwm txheej
Kem	Carbohydrate Cartridge rau dej (4.6x250mm)
ntes	RI
Kum Teem.	40 degree
Mobile theem	Dej: Acetonitrile (15:85)
Ntws	0.8ml / min
Txhaj vol.	20 ul

(1) Kev soj ntsuam ntau

Ntsuas qhov dav ntawm lub ncov tom qab 20ul txhaj tshuaj ntawm qhov kev sim thiab cov kuab tshuaj txheem

txhua, xam covcarob uasua ed extracthmoovpinitol cov ntsiab lus (%) nrog rau cov qauv hauv qab no.

Pinitol cov ntsiab lus (%)= (B/A) * purity ntawm tus qauv ib (%)

A: Tus nqi cheeb tsam ntawm tus qauv hnyav

B: Tus nqi ntawm qhov ntsuas qhov hnyav

Txhawm rau ntsuas cov ntsiab lus tseeb dua, rov ua qhov kev ntsuam xyuas saum toj no 3 ~ 5 zaug los txiav txim qhov kawg

pinitol cov ntsiab lus nrog tus nqi nruab nrab.

 

Moisture content analysis method

1) Tshav kub ntawm 105'C rau 4 teev nyob rau hauv qhov cub qhuav thiab ntsuas qhov hnyav ntawm chav tsev kub (a).

2) Ntsuas qhov tseeb 3g Carob Seed Extract Powder ntawm cov ntsiab lus ntawm qhov ntsuas qhov ntsuas tsis tu ncua (b).

3) Qhuav ntawm 105'c rau 4 xuab moos hauv qhov cub qhuav

4) Muab tso rau hauv chav sov li 30 feeb ntawm desiccator tom qab ziab

5) Ntsuas qhov ntsuas qhov hnyav li niaj zaus (c).

6) Cov ntawv xeem

Moisture (%) = b-c *100

                       b-a

a: Qhov hnyav ntawm qhov hnyav (g)

b: Qhov hnyav ntawm qhov hnyav thiab qhov hnyav (g)

c: Nyhav tom qab ziab (g)

 

D-pinitol yog dab tsi?

Carob Noob ExtractHmoov yog ib yam khoom tshwm sim uas nyob rau hauv chav kawm ntawm inositol, chav kawm ntawm cov tebchaw uas muaj cuaj isomers sib txawv. Inositol zoo ib yam li rau -membered monosaccharide (xws li qabzib). Txawm li cas los xij, nws tsis yog qab zib, tab sis yog cycloalditol. Zoo li monosaccharides, inositol yog ib feem ntawm tib neeg kev noj haus. Thiab muaj pov thawj tias nws tsis yog - lom. Pineol txawv ntawm lwm cov inositol uas nws muaj methyl ether pawg. Cov kev tshawb fawb tau pom tias pinitol muaj cov haujlwm lom neeg sib txawv dua li lwm cov inositol. Cov khoom ntuj tsim pinitol muaj nyob rau hauv qee yam legumes (xws li taum pauv), qee cov nroj tsuag, txiv hmab txiv ntoo, thiab ntoo thuv. Chemically, carob noob extract hmoov D-pinitol txhais tau tias yog inositol. Qhov zoo tshaj plaws ntawm pinitol yog nyob rau hauv carob pods. Carob ntoo tiv taus rau qhov tsis zoo ib puag ncig thiab feem ntau tsis tas yuav muaj kev kho mob tshwj xeeb xws li kev ua liaj ua teb hnyav lossis tshuaj tua kab.

 

Khoom:

Carob Noob ExtractHmoovD-Pinitol yog ib hom qab zib cawv uas muaj nyob hauv cov nroj tsuag. Cov hauv qab no yog nws cov khoom siv tshuaj thiab lub cev.

1. Cov khoom siv tshuaj

• Cov yam ntxwv ntawm tus qauv:

D-Pinitol Carob Seed Extract Powder belongs rau cyclohexane polyol compound. Nws cov qauv molecular yog tsib pawg hydroxyl thiab ib pawg methyl txuas nrog cyclohexane. Nws muaj cov qauv stereochemical tshwj xeeb. Nws muaj cov tshuaj lom neeg tshwj xeeb thiab kev ua haujlwm lom neeg.

• Kev ruaj ntseg:

Carob Noob ExtractHmoovD-Pinitol kuj ruaj khov nyob rau hauv ib puag ncig ib puag ncig. Txawm li cas los xij, nyob rau hauv cov xwm txheej hnyav xws li kub siab, muaj zog acid, thiab lub hauv paus muaj zog, nws cov qauv molecular yuav hloov. Piv txwv li, nyob rau hauv muaj zog acid tej yam kev mob, protonation ntawm hydroxyl pawg yuav tshwm sim, uas ua rau muaj kev hloov nyob rau hauv cov kev ua si thiab cov khoom ntawm lub molecule. Thaum rhuab ntawm qhov kub siab ntev ntev, qhov no yuav ua rau lub cev qhuav dej los tsim cov khoom uas muaj ob daim ntawv cog lus, thiab lwm yam.

• Reactivity

Cov ntau pawg hydroxyl hauv cov molecule ua D-Pinitol muaj cov tshuaj reactivity ntawm cawv. Nws tuaj yeem dhau los ua cov tshuaj tiv thaiv esterification nrog cov kua qaub los tsim cov ester sib txuas. Piv txwv li, cov tshuaj tiv thaiv nrog acetic acid tuaj yeem tsim D-Pinitol acetate.

Cov pab pawg hydroxyl ntawm D-Pinitol tuaj yeem oxidized. Piv txwv li, nyob rau hauv qhov kev ua ntawm oxidants tsim nyog, pawg hydroxyl tuaj yeem oxidized rau carbonyl lossis carboxyl pawg. Qhov no yuav tsim cov khoom oxidation nrog ntau lub zog thiab cov khoom.

Hydroxyl pawg kuj tuaj yeem koom nrog cov tshuaj tiv thaiv etherification. Nws reacts nrog lwm cov tebchaw uas muaj hydroxyl pawg lossis halogen atoms los tsim cov ether compounds.

 

2. Lub cev muaj zog

• Cov tsos mob:

Carob Noob ExtractHmoovfeem ntau yog dawb crystalline hmoov nrog ib tug ilv tsos. Nyob rau hauv lub microscope, nws cov crystals muaj ib tug tej yam zoo li thiab ib tug niaj hnub lattice qauv.

• ntxhiab thiab saj:

Carob Seed Extract Powder tsis muaj ntxhiab tsw, nrog lub teeb qab zib. Qhov qab zib no kuj yog me me. Nws tsis yog qab zib li cov suab thaj xws li sucrose.

• Solubility:

Carob Seed D-pinitol yooj yim soluble hauv dej thiab tuaj yeem yaj sai sai hauv dej los tsim cov tshuaj ntshiab. Qhov no yog vim muaj ntau pawg hydroxyl hauv nws cov molecules tuaj yeem tsim hydrogen bonds nrog dej molecules, yog li txhawb cov txheej txheem tawg. Nws kuj tseem muaj cov solubility zoo hauv qee qhov polar organic solvents xws li methanol thiab ethanol. Tab sis nws muaj qhov tsis zoo solubility nyob rau hauv uas tsis yog -polar organic solvents xws li roj av ether thiab benzene.

• Melting point

Lub melting point ntawm Carob Seed Extract Powder bulk D-pinitol feem ntau yog nyob nruab nrab ntawm 178-182℃. Thaum lub melting point yog mus txog, D-pinitol hloov los ntawm cov khoom mus rau cov kua. Qhov ntsuas kub no yog qhov ntsuas kub ntawm nws cov khoom hloov pauv hloov pauv thiab tuaj yeem siv rau nws qhov kev txheeb xyuas purity thiab kev tshawb fawb ntawm lub cev.

 

Factory & Pab Pawg:

 

Daim ntawv pov thawj

 

Ntim & Xa khoom

Cim npe nrov: Tuam Tshoj carob noob extract hmoov manufacturers, lwm tus neeg, Hoobkas