Indole-3-carbinol hmoov

Indole 3 Carbinol Powder Supplier:

Guan jie yog cov chaw tsim khoom lag luam ntawm ntau Indole 3 carbinol hmoov. Peb muaj raw khoom synthesis Rhiav thiab adheres nruj I3C hmoov zoo tus qauv. Cov tsos ntawm cov khoom no yog tawm dawb mus rau dawb crystalline hmoov. Guanjie tau nyob rau ntawm kab no rau ntau tshaj 20 xyoo, muaj ntau tshaj 15 engineers nyob rau hauv peb pab neeg. Peb tau txais ntau tshaj 14 patents. Qhov no ua kom ntseeg tau tias cov khoom peb muab tau zoo heev thiab kev ua haujlwm ruaj khov. Thiab peb muaj pab pawg muag khoom ntawm 30 tus neeg nyob hauv Suav teb los pab peb cov neeg siv khoom, nrog rau cov chaw ua haujlwm thiab cov tsev khaws khoom hauv Tebchaws Meskas thiab Tebchaws Askiv. Nws yuav yog qhov kev xaiv zoo rau koj los ua peb cov neeg siv khoom.

Indole-3-carbinol hmoov yog tsim los ntawm kev tawg ntawm glucosinolate glucobrassicin, uas yog tau los ntawm decomposition ntawm brassica glucoside thioside. Nws tuaj yeem pom nyob rau theem siab hauv cov zaub cruciferous xws li broccoli, zaub qhwv, zaub qhwv, brussels sprouts, collard zaub thiab kale. Nws kuj muaj nyob rau hauv cov khoom noj khoom haus. Nws khaws cia rau hauv qhov chaw txias & qhuav, Khaws kom deb ntawm lub teeb muaj zog thiab cua sov hauv qab 0-8 degree .

Cov kauj ruam ntawm cov khoom zoo:

◆ Peb yuav npaj cov qauv rau kev pom zoo;

◆ Tom qab tau txais kev pom zoo, peb pab neeg yuav teeb tsa cov txheej txheem khoom siv tes ua, thiab tsim ib daim duab sab hauv kom ua raws li nws;

◆ Thaum lub sijhawm tsim khoom, peb muaj FQC, IQC, IPQC thiab OQC los tswj qhov zoo.

COA

Flow Chart:

Indole-3-carbinol Test Sop

(Cov txheej txheem ua haujlwm txheem)

1. Lub Hom Phiaj: Tsim cov txheej txheem kev khiav hauj lwm ntawm Indole-3-Carbinol, xyuas kom meej qhov tseeb ntawm kev xeem.

2.Scope:Indole-3-carbinol tiav cov khoom

3. Lub luag haujlwm: QC

4.Test standard: Customer standard

5. Cov txheej txheem:

5.1 [Properties] Cov khoom no yog dawb los yog yuav luag dawb crystalline hmoov.

5.2. [Solubility] tsis yooj yim soluble hauv dej, soluble hauv ethanol (96 feem pua), me ntsis soluble hauv dichloromethane.

5.3 Check

5.4.1 Poob ntawm ziab: Tsis ntau tshaj 1.0 feem pua

5.4.1.1. Cov cuab yeej thiab cov tshuaj reagents: hluav taws xob sib npaug (d=0.01mg), hluav taws xob qhov cub ntsuas kub.

5.4.1.2. Cov kauj ruam:

Qhov hnyav li ntawm 100mg qauv, hnyav hauv lub khob qhov hnyav nrog qhov hnyav tas li, ziab ntawm 45 degree rau ob teev, tshem tawm mus rau lub desiccator ntawm chav tsev kub, ntsuas qhov hnyav, sau cov ntaub ntawv, tshem tawm mus txuas ntxiv 45 degree C qhov cub qhuav rau ob teev. Hloov lub tshuab ziab khaub ncaws mus rau chav tsev kub, ntsuas cov ntaub ntawv sau tseg kom raug. Ob qhov kev ua yuam kev yuav tsum tsawg dua 0.3mg.

5.5 Cov ntsiab lus tus qauv xav tau: 98 feem pua ​​-102 feem pua ​​(raws li qhuav)

Instrument thiab reagent

Electronic tshuav nyiaj li cas (d=0.01mg), HPLC (siab ua kua chromatography), methanol (HPLC qib),

purified dej, triethylamine (AR).

6. Chromatographic tej yam kev mob

Sab: Xtimate C18, 4.6X250mm 5μm.

Mobile theem: methanol: dej (60:40), triethylamine hloov mus rau pH=8.0, degassing.

Wavelength: 254nm Kem kub: 30 degree

Tus nqi ntws: 1.0ml / min Txhaj ntim: 20ul.

Cov txheej txheem ntsuas: Contrast d: Dissolve 10mg Indole-3-Carbinol txheem khoom rau hauv 25ml volumetric hwj, mus rau qhov sib piv d6 zaug RSD feem pua<2.0%, accurately weighed two samples to be tested 10mg, respectively, to 25 ml brown volumetric flask, dissolved in methanol, ultrasound 5min at room temperature for injection.

7. Cov ntaub ntawv kaw thiab suav: txheej txheem txheej txheem sab nraud

Raws li —— Sample ncov cheeb tsam

WS —Sample hnyav

AR — Tus qauv ncov cheeb tsam

WR —— Txheem cov khoom hnyav

A-Sample poob ntawm ziab

CR — Cov ntsiab lus txheem

8. Kev ceeb toom ua haujlwm:

1.Cov khoom no yog rhiab rau lub teeb thiab kub, nrog rau qhov kub thiab txias thiab lub sij hawm. Kev sim yuav tsum ceev li sai tau, thiab yuav tsum zam lub teeb thiab huab cua.

2.Cov khoom khaws cia hauv lub thawv kaw, tiv thaiv lub teeb, khaws cia hauv qab -10 degree C lossis tsawg dua.

HPLC digital fingerprint

Stability Test Methods

● Taw qhia:

Lub hom phiaj ntawm kev ntsuas kev ruaj ntseg yog los muab cov pov thawj ntawm qhov zoo ntawm Indole-3-Carbinol sib txawv nrog lub sij hawm nyob rau hauv qhov kub thiab av noo thiab mus rau

tsim kom pom zoo cia tej yam kev mob, retest lub sij hawm thiab txee lub neej.

● Lub luag haujlwm:

QA / QC Tus Thawj Coj yog lub luag haujlwm rau kev tshawb fawb kev ruaj ntseg thiab tseem yog lub luag haujlwm rau cov qauv kev ruaj ntseg soj ntsuam nrog rau kev saib xyuas cov ntaub ntawv kev pab cuam.

● Cov txheej txheem thiab tsim kev kawm ruaj khov:

● Kev Kawm Ntev Ntev:

Cov qauv ntawm Indole-3-Carbinol raug kaw nruj nreem nyob rau hauv cov hnab polyethylene, kaw rau hauv hnab PE thiab ntim rau hauv cov thawv aluminium. Lawv khaws cia nyob rau hauv lub sij hawm ntev ntawm 252 degree kub thiab 60 ± 5 feem pua ​​​​cov av noo raws li ICH / FDA cov lus qhia. Peb cov txheej txheem sib law liag validation batch thiab ib batch txhua txhua xyoo yog coj mus kuaj thiab muab tso rau lub sij hawm ntev kev ruaj ntseg xeem. Tom qab kev soj ntsuam thawj zaug, cov qauv no yuav raug tshuaj xyuas ntawm 3, 6, 9, 12 thiab 15 lub hlis. Cov txiaj ntsig rau hnub no qhia tau tias Indole-3-Carbinol ruaj khov ntawm 25 ± 2 degree qhov kub thiab txias 60 ± 5 feem pua.

Accelerated Studies:

Cov qauv ntawm Indole-3-Carbinol tau muab tso rau hauv hnab polyethylene, ntim rau hauv hnab PE, ntim rau hauv cov thawv txhuas thiab khaws cia ntawm 40 ± 2 degree thiab 75 ± 5 feem pua ​​​​ntawm cov av noo. Peb cov batch sib law liag raug coj mus kuaj. Tom qab kev soj ntsuam thawj zaug, cov qauv no tau txheeb xyuas ntawm 1, 2, 3 thiab 6 lub hlis raws li ICH Cov Lus Qhia. Cov txiaj ntsig rau hnub no qhia tau tias Indole-3-Carbinol ruaj khov ntawm 40 ± 2 degree kub thiab 75 ± 5 feem pua ​​​​ntawm cov av noo.

Accelerated Studies:

Cov qauv ntawm Indole-3-Carbinol tau muab tso rau hauv hnab polyethylene, ntim rau hauv hnab PE, ntim rau hauv cov thawv txhuas thiab khaws cia ntawm 40 ± 2 degree thiab 75 ± 5 feem pua ​​​​ntawm cov av noo. Peb cov batch sib law liag raug coj mus kuaj. Tom qab kev soj ntsuam thawj zaug, cov qauv no tau txheeb xyuas ntawm 1, 2, 3 thiab 6 lub hlis raws li ICH Cov Lus Qhia. Cov txiaj ntsig rau hnub no qhia tau tias Indole-3-Carbinol ruaj khov ntawm 40 ± 2 degree kub thiab 75 ± 5 feem pua ​​​​ntawm cov av noo.

Kev Kawm Degradation:
Lub hom phiaj ntawm kev kawm degradation yog los txiav txim seb HPLC txoj kev siv los ntawm peb lub chaw rau cov khoom tso tawm thiab kev tshawb fawb kev ruaj ntseg yuav ntes cov impurities thiab vim li ntawd yog qhov qhia txog kev ruaj ntseg. Peb ntau ntau ntawm kev ruaj ntseg, IC140910, IC140926, IC140930 raug xaiv thiab cov qauv ntawm cov ntau no tau raug:
a. Sodium Hydroxide, 0.00001 N
b. Hydrochloric Acid, 0.04 N
c. Hydrogen peroxide, 10 feem pua
d. Kub ntawm 60 degree
e. Ultraviolet lub teeb

Daim ntawv thov

◆ Tshuaj Field:

Raws li cov kws kho mob nruab nrab, Indole-3-carbinol hmoov yog cov tshuaj tiv thaiv kabmob kheesxaws zoo tshaj plaws uas tsis muaj tshuaj lom thiab ua haujlwm siab. Nws tuaj yeem txo qhov kev pheej hmoo ntawm kev mob qog noj ntshav thiab inhibit qog nqaij hlav cancer ntawm lub mis, mob caj pas, thiab lwm yam qog nqaij hlav;

◆ Chaw Kho Mob:

Raws li tus neeg sawv cev antioxidant thiab tiv thaiv kev laus, nws tuaj yeem tshem tawm cov dawb radicals, txhawb cov cell metabolism, tiv thaiv kev laus thiab kev tu tawv nqaij. Thiab nws tseem tuaj yeem txo cov kab mob hauv lub plawv, hyperglycemia, thiab Alzheimer's kab mob, thiab ua rau lub neej ntev.

◆ Cosmetics Field:

I3C tuaj yeem ntxiv rau cov tshuaj pleev ib ce, kho tawv nqaij, thiab tiv thaiv kev laus.

Muaj nuj nqi

◆ Kev tswj cov tshuaj estrogen

Indole-3-methanol inhibits estrogen synthesis, blocks estrogen-related pathways, thiab inhibits estrogen-induced cell proliferation.Vim tias muaj cov txheej txheem no, indole-3-methanol tau xav tias yuav siv los tswj cov kab mob cuam tshuam nrog hyperestrogens.

◆ Indole-3-carbinol hmoov yog siv rau kev kho mob fibromyalgia, virus-induced intralarynx qog (laryngeal papillomatosis), virus-induced respiratory tract qog (papillomatosis), kev loj hlob txawv txav ntawm ncauj tsev menyuam hlwb (cervical dysplasia), systemic dysplasia Lupus (SLE).

Cov khoom tsim nyog

Indole-3-carbinol Bulk Powder yog tsim nyob rau hauv ib qho chaw ua haujlwm huv si thiab txhua kauj ruam ntawm cov txheej txheem yog ua los ntawm cov kws tshaj lij. Ob qhov txheej txheem ntawm kev tsim khoom thiab cov khoom nws tus kheej ua tau raws li txhua tus qauv thoob ntiaj teb. Thiab yog tias koj xav tau peb tsab ntawv ceeb toom, peb tuaj yeem muab rau koj.

Peb lub Hoobkas:

Muaj ob lub chaw tsim khoom hauv Baoji nroog thiab Shangluo City, Guanjie cov chaw ua haujlwm npog thaj tsam ntawm 7000㎡, suav nrog GMP tus qauv rhiav ntawm 2000㎡.

Daim ntawv pov thawj

Peb tau txais NON-GMO los ntawm Pony test thoob ntiaj teb pab pawg. Thiab peb tau txais ntawv pov thawj txog HALAAL, ISO 9001, ISO 22000, Kosher, PAHS, SC thiab lwm yam.

Pob & Warehouse:

Kev xa khoom xa tuaj:

DHL, hiav txwv freight, FEDEX, koj tuaj yeem xaiv.

Cim npe nrov: indole-3-carbinol hmoov, Tuam Tshoj indole-3-carbinol hmoov manufacturers, lwm tus neeg, Hoobkas